background: improving the performance of hiv diagnosis assays is one of the most important ways to reduce hiv transmission. because of the high mutation rate of hiv, it is critical to use the conserved proteins to develop diagnostic immunoassay methods. because integrase is one of the most conserved proteins of hiv, it may be a good target for this purpose. in this paper cloning, purification a...

The bovine lentivirus, known as bovine immunodeficiency-like virus (BIV), is genetically, structurally, and antigenically related to human immunodeficiency virus type 1 (HIV-1). It is not known whether sera from persons exposed to BIV proteins would show either positive or indeterminate reactivity on HIV-1 antibody tests. We used a BIV Western blot (immunoblot) analysis to examine human sera ch...

Mammals have co-evolved with lentiviruses for a long time. As evidence, viral infectivity factor (Vif), encoded by lentiviruses, antagonizes the anti-viral action of cellular APOBEC3 of their hosts. Here, we address the co-evolutionary dynamics of bovine APOBEC3 and the following two bovine lentiviruses: bovine immunodeficiency virus (BIV) and Jembrana disease virus (JDV). We determined the seq...

The present study was designed to evaluate the effect of bovine immunodeficiency virus (BIV) infection on immune functions and possible interactions between BIV and other bovine viruses in calves. Ten calves were inoculated intravenously with BIV, and five served as controls. An increased lymphocyte proliferation to BIV gag protein was demonstrated 2 to 6 weeks after BIV inoculation (P < 0.05)....

introduction: oral manifestations can be the first signs of human immunodeficiency virus/acquired immunodeficiency syndrome (hiv/aids) and a useful marker for the progression of this disease. the present study aimed to determine the prevalence of oral manifestations and examine their relationship with socio-demographic factors in hiv-positive patients in the health centers affiliated to zahedan...

background: because dental staff members are in continuous contact with blood and contaminated fluids of patients, they are considered as a high risk group. their knowledge about standard precautions is thus important in preventing infectious diseases such as hepatitis and human immunodeficiency virus (hiv). the purpose of this study was to estimate the injuries that occur in dental staff and t...

current mainstay of treatment for human immunodeficiency virus (hiv)-infected patients is highly active antiretroviral therapy (haart) but little is known about the long-term clinical outcome for hiv-infected patients who have received haart. determining factors associated with longterm survival in the course of treatment may allow modification to be made for patients who are at a greater risk ...

a rapid and sensitive reverse transcription polymerase chain reaction (rt-pcr) and nested-pcr were used to detect bovine viral diarrhea virus 1 (bvdv-1) in bull semen. selected primers could amplify a part of the 5´utr of the bvdv genome. a 294 bp dna fragment was amplified and specificity of the results was confirmed by direct sequencing of the pcr product. prior to rna extraction, the seminal...