Publication bias is the preferential publication of research with positive results, and is a threat to the validity of medical literature. Preliminary evidence suggests that research in blood and marrow transplantation (BMT) lacks publication bias. We evaluated publication bias at an international conference, the 2006 Center for International Blood and Marrow Transplant Research (CIBMTR)/Americ...

INTRODUCTION A fracture mechanics based approach has been recently proposed to measure the changes in fracture toughness of small animal bones due to aging, disease, and treatments for osteoporosis [1-3]. In contrast to standard strength tests, such tests require a smaller sample size [2] and provide a measure of material level changes [2,3]. Here we present a complementary computational approa...

Reference point indentation (RPI) was developed to measure material-level mechanical properties of bone in vivo. Studies using RPI in vivo have discriminated between human subjects with previous skeletal fractures and those without and among dogs given different anti-remodeling drugs. Recently, this technology was extended to rats, providing the first in vivo data for rodents. The goal of the p...

Shiramizu K; Lovric V; Leung AMD; +Walsh WR Surgical & Orthopaedic Research Laboratories, University of New South Wales, Sydney, Australia [email protected] INTRODUCTION Deep infection after total joint replacement is a severe complication, and the use of antibiotic-loaded bone cement as a joint spacer is an established and efficient treatment method to treat infected arthroplasties. When pre...

Bone histology of decalcified or undecalcified samples depends on the investigation. However, in research each method provides different information to answer the scientific question. Decalcification is the first step after sample fixation and governs what analysis is later feasible on the sections. Besides, decalcification is favored for immunostaining and in situ hybridization. Otherwise, sam...

Structural bone allografts have become an alternative in the treatment of limb bone tumours with a chance of limb-saving surgery. We present an observational retrospective study on the use of structural bone allografts in bone tumours of the long bones in our hospital between January 1993 and January 2010, with a sample of 37 patients subjected to this surgical technique. After obtaining clinic...

Abstract Background Optimal timing of bone culture obtainment relative to antibiotic initiation in diabetic foot osteomyelitis is unknown. This study aims determine whether administration prior sample collection affects microbiological yield. Methods was a single-center retrospective study. Patients at least 18 years old admitted for management were included. included the had an evaluable and m...