نتایج جستجو برای: bone morphogenetic protein 4
تعداد نتایج: 2612758 فیلتر نتایج به سال:
BACKGROUND It has been studied that the distribution of bone morphogenetic protein 2 is regular under bone defect situation. OBJECTIVE To observe the expression of bone morphogenetic protein 2 in rabbit radial defect site with different lengths. METHODS Forty-eight New Zealand rabbits were divided into two groups randomly. 0.5 cm bone defect and 3.0 cm bone defect were made by wire saw at t...
background :delayed ::::union::::, non::::union::::, and mechanical failure is still problems encountered in limb salvage surgery (lss) using extracorporeal irradiation (eci). this study aimed to determine whether bone marrow mesenchymal stem cells (msc) and recombinant human bone morphogenetic protein-2 (rhbmp-2) improve host-graft ::::union:::: after osteotomy and also increase its mechanical...
Bone is a major storage site for TGFbeta superfamily members, including TGFbeta and bone morphogenetic proteins. It is believed that these cytokines are released from bone during bone resorption. Recent studies have shown that both RANKL and macrophage colony-stimulating factor are two essential factors produced by osteoblasts for inducing osteoclast differentiation. In the present study we exa...
Prostate cancer is the most commonly diagnosed malignancy in men and is often associated with bone metastases. Prostate cancer bone lesions can be lytic or schlerotic, with the latter predominating. Bone morphogenetic proteins (BMPs) are a family of growth factors, which may play a role in the formation of prostate cancer osteoblastic bone metastases. This study evaluated the effects of BMPs on...
STUDY DESIGN An in vitro experiment to determine the molecular and cellular effect of recombinant human bone morphogenetic protein-2 on cultured rat intervertebral disc cells was performed. OBJECTIVES To determine the effect of recombinant human bone morphogenetic protein-2 on cell proliferation, production of sulfated-glycosaminoglycan, and the expression of genes specific for chondrocytes (...
Introduction & Objective: Bone morphogenetic proteins are a group of cytokines that belongs to superfamily TGFβ. These proteins play an important role in evolution of many of organs and tissues through germinal period followed by amending and rebuilding of bone tissue and car-tilage. The aim of this study was to clone and expression analysis of BMP-2 gene in E. coli bacteria. Materials & Method...
STUDY DESIGN A literature review was conducted. OBJECTIVES To review the discovery of the bone morphogenetic proteins and describe the bone morphogenetic protein products that will or may be available for clinical use. SUMMARY OF BACKGROUND DATA Bone morphogenetic proteins comprise the osteoinductive component of several tissue engineering products in late-stage development as replacements ...
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