PURPOSE/OBJECTIVES To describe the role of the oncology nurse practitioner in the performance of bone marrow aspiration and biopsy and discuss the indications and diagnostic value of bone marrow examination. DATA SOURCES Published articles, textbooks, personal experience. DATA SYNTHESIS Bone marrow examination is useful in the diagnosis of many nonhematologic and hematologic conditions. Hav...

Objective: To find out the frequency of involvement of bone marrow by non – haematological disorders in our institution and to evaluate the role of bone marrow aspiration and biopsy in diagnosing these disorders. Materials & Methods: It was a retrospective study that extended from January 2013 to December 2016. A total of 339 bone marrow aspirates and trephine biopsies were performed during thi...

The bone marrow examination is invaluable in the diagnosis of certain haematological and non haematological conditions. The diagnosis of haematological disorders is achieved mainly by the examination of peripheral blood and bone marrow aspirate smears. Although bone marrow histology can provide additional information, for many technical reasons, trephines are not so popular and their diagnostic...

Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99mTc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bo...

The bone marrow is one of the largest organs in the human body (Lund, 2000). It is the major hematopoietic organ and is important as both a primary and secondary lymphoid organ. Since it is a potential target organ of various disorders, evaluation of blood and bone marrow is an important component of any overall assessment studies. Bone marrow evaluation studies provide information about bone m...

BACKGROUND Attempts to analyze bone marrow aspirates have been reported with the use of several automated blood cell counters, but sufficient accuracy in examination is not acquired yet. Major problems have included difficulties in correctly differentiating various immature cells and interference by lipid in bone marrow aspirates. The goal of this study was to solve these problems to attain mor...

Objective(s): Intracerebral injection of bone marrow stromal cells (BMSCs) is being investigated as a therapeutic tool to prevent Alzheimer's disease (AD). Our aim was to investigate the effects of BMSCs by intrathecal injection in AD rat model. Materials and Methods: BMSCs were obtained from the bone marrow of Wistar rat and transplanted into AD rat model via intrathecal injection. The rat mod...

Background: Hematological disorders are found commonly in the general population existing on both ends of spectrum with minute like iron deficiency anemia to as severe bone marrow infiltration Objective: To assess frequency hematological malignancies based bone-marrow aspiration and trephine biopsy patients presenting tertiary care hospital Methodology: The current study was cross-section descr...