Granulocyte colony-stimulating factor (G-CSF) is a hematopoietic cytokine which controls the differentiation and growth of hematopoietic cells in the bone marrow. We report a severe aplastic anemia (SAA) patient with false-negative 99mTc sodium phytate bone marrow imaging findings under concurrent G-CSF therapy. The first bone marrow imaging showed a normal bone marrow activity. However, the bo...

The fatty acid composition of bone marrow lipid was studied in 10 normal individuals and in 90 patients with a hematologic disorders. Simultaneously , the fatty acid composition of bone marrow was studied in rabbits and dogs which were injected with nitromin and cortisone, and others which were irradiated and subjected to periodic venesection. The fatty acid composition of normal human bone mar...

Objective: To evaluate the frequency of involvement of bone marrow with non-haematologic disorders and to observe the significance of bone marrow examination in establishing primary diagnosis of the same. Methods: It was a descriptive study that extended from January 2003 to September 2005. A total of 4569 bone marrow aspirate and trephines were reported during this period. Only the non-haemato...

background: hematological abnormalities are a common complication of hiv infection and occur in all stages of the infection. these abnormalities increase as the disease advances. we aimed to evaluate the diagnostic utility of bone marrow sampling in hiv-positive patients. methods: 40 hiv-infected individuals were screened for hematological abnormalities. investigations such as iron studies, hem...

Myelodysplastic syndrome (MDS) is a set of clonal bone marrow diseases in children that are characterised by peripheral cytopenia, dysplastic alterations the marrow, and inefficient hematopoiesis. MDS uncommon children, with just 1-4 occurrences per million afflicted. Adults, particularly elderly, more susceptible to disease. Some hereditary disorders, such as Fanconi's anaemia, Shwachman's, Do...

eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (bmt) from hla-matched siblings during the period of 1990 to 1996. the conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. antilymphocyte globulin (alg) and cyclosporine were used for rejection and acute gvhd prophylaxis, respective...

introduction: as an inherited neurodegenerative disease, huntington's disease is accompanied with wide neuronal degeneration in neostriatum and neocortex. progress of the disease causes disabling clinical effects on movements, recognition and physiology of the body, and finally results in death. at this stage of knowledge we are, there is no effective therapeutic strategy for diminishing t...

acute myeloid leukemia (aml-m7) is a type of pediatric aml accounting for 3–10% of primary childhood aml and children may present with a broad variety of symptoms including low-grade fever, diarrhea, easy bruising, failure to gain weight and life-threatening conditions. we report a rare case of aml .a 26-month-old boy who presented with weakness and fatigue. he was diagnosed as a case of amlm-7...