Consumers who had purchased farm products from both quarantined and nonquarantined farms were examined during the cross-sectional clinical survey of 1,029 Michigan residents. Since PBB had inadvertently contaminated cattle and other farm animals, ingestion of meat, milk, eggs and other farm products was thought to have possibly resulted in significant PBB body burdens in some consumers. Finding...

The work addresses current knowledge gaps regarding causes for correlations between environmental and biomarker measurements and explores the underappreciated role of variability in disaggregating exposure attributes that contribute to biomarker levels. Our simulation-based study considers variability in environmental and food measurements, the relative contribution of various exposure sources ...

Measurements of urinary proteins, blood and urinary cadmium, and in vivo kidney and liver cadmium have been made for a group of workers at several times between 1981 and 1990. The possibility of the introduction of measurement artifacts due to the use of different in vivo measurement systems has been assessed and is considered to be small. Changes in cadmium body burden with time have been stud...

The bioaccumulation of 10 metals in five fish species was experimentally evaluated following exposure to dietary or aqueous metal at environmentally realistic metal concentrations. A biokinetic model showed that, with few exceptions, >90% of a fish’s metal body burden was obtained from diet. Regulatory bodies need to consider these findings in setting appropriate water quality criteria. Metal u...

A food web bioaccumulation model was used to compare transport and fate of polychorinated biphenyls (PCB) congeners in three food webs in the Laurentian Great Lakes of North America. The model was used to quantify the contribution of sediment-derived and freely dissolved PCBs to the body burden of aquatic biota. In eastern Lake Erie (OH, USA), almost 100% of the chemical body burden of biota or...