نتایج جستجو برای: bocs
تعداد نتایج: 294 فیلتر نتایج به سال:
هدف: هدف پژوهش حاضر، بررسی پایایی و روایی نسخه فارسی مقیاس وسواسی- اجباری ییل- براون (y-bocs) بود. روش: 140 بیمار مبتلا به اختلال وسواسی- اجباری (ocd)، بهعنوان گروه آزمایش و 30 فرد سالم، بهعنوان گروه گواه، بهصورت در دسترس انتخاب شدند. برای گردآوری دادهها، افزون بر y-bocs، مصاحبه بالینی ساختاریافته برای اختلالهای محور i در dsm-iv (scid-i) و خردهمقیاس وسواسی- اجباری سیاهه 90 گویهای نشانهه...
OBJECTIVE To evaluate the overall effect of D-cycloserine (DCS) augmentation on exposure and response prevention (ERP) therapy for obsessive-compulsive disorder (OCD). METHODS Clinical studies on the effect of DCS augmentation on ERP therapy for OCD compared to placebo were included for meta analysis. The primary outcome was the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). Meta-analyses we...
هدف: مقایسه اثربخشی کوئیتیاپین و ریسپریدون در درمان تکمیلی بیماران مبتلا به اختلال وسواسی- جبری مقاوم به درمان. روش: در این پژوهش که یک مطالعه دوسوکور تصادفی می باشد، 76 بیمار با اختلال وسواسی- جبری به مدت 12 هفته ssri دریافت کردند.40 بیمار مقاوم به درمان بودند که به دو گروه تقسیم شدند و تحت درمان تکمیلی با کوئیتیاپین یا ریسپریدون قرار گرفتند . پاسخ به درمان بعد 4 هفته با ابزار y-bocs ارزیابی ...
AIM Several lines of evidence implicate glutamatergic dysfunction in the pathophysiology of obsessive-compulsive disorder (OCD), presenting this neurotransmitter as a target for the development of novel pharmacotherapy. The objective of this study was to assess the efficacy of minocycline as an augmentative agent to fluvoxamine in the treatment of patients with OCD. METHODS One hundred and tw...
The current data suggest that up to 50% of patients with schizophrenia have obsessive-compulsive (OC) symptoms coexisting with psychosis and between 7.8 and 46% of schizophrenia patients also have full-blown obsessive-compulsive disorder (OCD). The aim of this study was to examine the efficacy of the most selective serotonin reuptake inhibitor escitalopram in the management of OCD in schizophre...
BACKGROUND This open trial was conducted to evaluate the effectiveness of intravenous clomipramine (CMI) in refractory obsessive-compulsive disorder (OCD). METHODS Thirty OCD poor responders to previous multiple trials of anti-obsessive medications were selected and admitted to the hospital. Severity of the illness and response to treatment were primarily assessed by the Yale-Brown Obsessive ...
BACKGROUND High-frequency bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) is a promising treatment in refractory obsessive-compulsive disorder (OCD). METHOD Using the crossover, randomized, and double-blind procedure adopted by the STOC study, 10 patients treated with high-frequency bilateral STN DBS underwent am 18-fluorodeoxyglucose positron emission tomography (PET) invest...
OBJECTIVES The clinical presentation of pediatric obsessive-compulsive disorder (OCD) is heterogeneous, which is a stumbling block to understanding pathophysiology and to developing new treatments. A major shift in psychiatry, embodied in the Research Domain Criteria (RDoC) initiative of National Institute of Mental Health, recognizes the pitfalls of categorizing mental illnesses using diagnost...
BACKGROUND In 2006, the National Institute of Clinical and Health Excellence (NICE) guidelines for Obsessive Compulsive Disorder (OCD) recommended anti-psychotics as a class for SSRI treatment resistant OCD. The article aims to systematically review and conduct a meta-analysis on the clinical effectiveness of atypical anti-psychotics augmenting an SSRI. METHODS Studies that were double-blind ...
Beginning with DSM-III-R, the condition of an intact insight towards obsessive-compulsive symptoms, which was essential for the classical definition of obsessivecompulsive neurosis, has been removed, permitting inclusion of cases with poor insight. A total of 94 cases who met DSM-III-R criteria for obsessive-compulsive disorder were included in this study. The Structured Clinical Interview for ...
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