We demonstrate the efficient separation of blood cells from millilitre volumes of whole blood in minutes using a simple gravity sedimentation device. Blood cell and plasma separation is often the initial step in clinical diagnostics, and reliable separation techniques have remained a major obstacle for the success of point-of-care or remote diagnostics. Unlike plasma collection devices that rel...

For a long tine I had been looking in vain for a micro method of blood sedimentation convenient for babies and exprimental animals until I myself contrived one, which will be reported elsewhere in this journal. Soon after the completion of my micro method I took up the problem of the present paper, because I presumed a certain relation between the sedimentation rate of blood corpuscles and the ...

Electrophoretic studies and erythrocyte sedimentation rate measurements were carried out on normal and pathological human blood. An increase in alpha globulin levels appears to take place, as well as an increase in sedimentation rates, when there is present any considerable inflammation or tissue destruction, irrespective of its cause. A graphic correlation is presented between sedimentation ra...

the blood biochemical parameters were investigated in a yak (bos grunniens l) after intravenous administration of 5 mg/kg enrofloxacin. blood samples were collected from the jugular vein daily for 5 days after the drug administration. heparinized bloods were collected for mean corpuscular volume (mcv), erythrocyte sedimentation rate (esr), hemoglubin (hb) estimation and serum was collected for ...

Determination of the stoichiometry of macromolecular assemblies is fundamental to an understanding of how they function. Many different biophysical methodologies may be used to determine stoichiometry. In the past, both sedimentation equilibrium and sedimentation velocity analytical ultracentrifugation have been employed to determine component stoichiometries. Recently, a method of globally ana...

Serum C-reactive protein (CRP) and the erythrocyte sedimentation rate (ESR) were compared in 241 patients with rheumatoid arthritis (RA). There was a positive linear correlation between the 2 measurements with a high degree of variability. Neither age nor duration of RA had a detectable influence. The relationship between CRP and ESR was, however, altered by treatment with gold, penicillamine, ...

We describe a computational analysis method to evaluate the efficacy of immunomagnetic rare cell separation from non-Newtonian particulate blood flow. The core procedure proposed here is calculation of local viscosity distributions induced by red blood cell (RBC) sedimentation. Numerical calculation methods have previously been introduced to simulate particulate behavior of individual RBCs. How...