BACKGROUND Chronic lymphoedema is one of the most frequent and debilitating complications after surgical and radiological tumour treatment. Prevention and therapy of lymphoedema is therefore an important problem of the rehabilitation of those patients. AIM To investigate whether chronic lymphoedema results in increased oxidative stress. DESIGN Prospective case-control study. METHODS We ob...

Lipid peroxidation is the oxidative deterioration of polyunsaturated fatty acids (PUFAs), which is a free radical related process. Studies showed that reactive oxygen species (ROS) are involved in a diversity of biological phenomena including atherosclerosis, neurodegenerative diseases, carcinogenesis etc. ROS and other pro-oxidant agents have the capacity to exhibit oxidative decomposition of ...

objective: oxidative stress is the result of an imbalance between free radical production and antioxidant defenses of the body. the use of antioxidants can have preventive effects in diabetes. the present study aims to show the effects of biarum bovei extracts on lipid profile, lipid peroxidation in streptozocin induced diabetic male rats. materials and methods: animals were randomly assigned t...

A drug may cause alteration in blood-lipid profile and induce lipid peroxidation phenomena on administration in the body. Antioxidant may play beneficial role to control the negative alteration in lipid profile and lipid peroxidation. In view of this context, the present in vivo study was carried out to evaluate the role of ascorbic acid as antioxidant on netilmicin-induced alteration of blood ...

Despite extensive research, the effects of alpha-tocopherol supplementation remain controversial. Few studies have been focused on obese and overweight people. We examined the effects of alpha-tocopherol (AT) on the oxidative status and metabolic profile in overweight women. Sixteen overweight women between the ages of 40-60 years old, received AT, 800 IU/day during 12 weeks, followed by a 6-we...

Objective(s) Recent studies revealed the neuroprotective effects of epigallocatechin gallate (EGCG) on a variety of neural injury .The purpose of this study was to determine the effects of EGCG on the tissue lipid peroxidation after spinal cord injury (SCI). Materials and Methods Rats were randomly divided into four groups of 7 rats each as follows: sham-operated group, trauma group, and EGC...

AIM The aim of this study was to evaluate the effect of radiotherapy on lipid peroxidation, total sulfhydryl groups (RSH) and nitric oxide (NO radical) levels in plasma of cancer patients treated on different anatomic sites, and to compare the results with control subjects. METHODS 89 patients with various malignancies and 33 healthy control subjects were recruited for the study. Cancer patie...