We determined the effect of perfusion pressure on the distribution of blood flow within the renal cortex of the anesthetized dog. Total blood flow to the denervated kidney was measured by an electromagnetic flowmeter and perfusion pressure was manipulated over the autoregulatory range (136 to 81 mm Hg) by an aortic clamp. Distribution of cortical blood flow was determined by the radioactive mic...

Coronary artery disease (CAD) is an important cause of morbidity and mortality worldwide. Perfusion abnormalities precede wall motion abnormalities, ECG changes, angina in the etiology CAD. myocardial perfusion imaging (MPI) can detect alterations due to pathology at sites such as endothelium, microvasculature, epicardial coronary arteries. Thus, it measures universal burden ischemic heart (IHD...

In order to survive, all cells need a consistent supply of blood to deliver oxygen and nutrients and to remove wastes. When the blood supply or perfusion is impaired, ischemia develops and can progress to necrosis, if prolonged. For this reason, perfusion is a critical concept for nurses to understand and incorporate into practice. The purpose of this concept analysis is to help the nurse acqui...

Regional myocardial flow distributions in Langendorff rat hearts under Tyrode and blood perfusion were assessed by tracer digital radiography (100-microm resolution). Flow distributions during baseline and maximal hyperemia following a 60-s flow cessation were evaluated by the coefficient of variation of regional flows (CV; related to global flow heterogeneity) and the correlation between adjac...

Displacement of the left ventricular diastolic pressure-dimension relationship (change in compliance) has been observed with alterations in coronary perfusion pressure. The relative contribution of coronary (myocardial) blood flow, as compared with the perfusion pressure at which flow occurs, was studied in 10 dogs during diastolic relaxation by potassium arrest during cardiopulmonary bypass. T...

The abnormal vasculature of the tumor microenvironment supports progression and resistance to treatment. Judicious application of antiangiogenic therapy may normalize the structure and function of the tumor vasculature, promoting improved blood perfusion. However, direct clinical evidence is lacking for improvements in blood perfusion after antiangiogenic therapy. In this study, we used MRI to ...

Background. In traditional Chinese medicine acupuncture manipulation is one of the key factors that affect the curative results of acupuncture and more and more researches focus on how the different acupuncture manipulation techniques influence microcirculation nowadays. In this paper we demonstrate the different influences of lift-thrust reinforcing and reducing on blood perfusion. Method. The...