نتایج جستجو برای: blocking antibodies

تعداد نتایج: 206867  

Journal: :Biological & clinical sciences research journal 2023

The study's objective was to investigate the antibody responses and fetal maternal adverse effects of Sinopharm vaccine. A prospective study conducted in Gynaecology Department LUMHS Hospital Jamshoro, Hyderabad, Multan DG Khan from January 2021 2022. total 90 women were included who administered Sinopharm. 3/90 (3.3%) received shots 1st trimester, 56/90 (62%) 2nd trimester 31/90 (34%) 3rd trim...

2015
Al Qaoud Khaled Yousef Sana Rawashdeh Abdulrahman Khalil Raida Abdel Hafez Sami

PURPOSE The production of camel heavy-chain antihuman IgE (huIgE) that has the potential to block IgE-FcεRI interaction and histamine release by basophils. METHODS Camels were immunized with a synthetic loop peptide (SLP) designed in a multiple antigen peptide system (MAPS) forming SLP-MAPS immunogen. Camel polyclonal antibodies (PCAs) were produced, purified, characterized using Protein A & ...

Journal: :FEBS letters 2014
Chrisann Kyi Michael A Postow

Cancers can be recognized by the immune system, and the immune system may regulate and even eliminate tumors. The development of checkpoint blocking antibodies, such as those directed against cytotoxic T-lymphocyte antigen 4 (CTLA-4) and programmed death 1 receptor (PD-1), have demonstrated significant recent promise in the treatment of an expanding list of malignancies. While both CTLA-4 and P...

Journal: :Clinical and experimental rheumatology 2010
S Arends H R Lebbink A Spoorenberg L B Bungener C Roozendaal E van der Veer P M Houtman E N Griep P C Limburg C G M Kallenberg G J Wolbink E Brouwer

OBJECTIVES To investigate the influence of antibody formation to TNF-α blocking agents on the clinical response in AS patients treated with infliximab (IFX), etanercept (ETA), or adalimumab (ADA), and to investigate the development of ANA, ANCA, and anti-dsDNA antibodies in association with the formation of antibodies to TNF-α blocking agents. METHODS Consecutive AS outpatients with active di...

2017
Lucy K. Shewell Freda E.-C Jen Michael P. Jennings

The emergence of multi-drug resistant Neisseria gonorrhoeae has generated an urgent need for novel therapies or a vaccine to prevent gonococcal disease. In this study we investigate the potential of targeting the surface exposed nitrite reductase, AniA, to block activity by producing functional blocking antibodies. AniA activity is essential for anaerobic growth and biofilm formation of N. gono...

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