نتایج جستجو برای: bkv subtypesubgroup

تعداد نتایج: 379  

Journal: :Memorias do Instituto Oswaldo Cruz 2011
Daisy Maria Machado Maria Cristina Fink Cláudio Sérgio Pannuti Regina Célia de Menezes Succi Alessandra Aparecida Machado Fabiana Bononi do Carmo Aída de Fátima Barbosa Gouvêa Paulo Roberto Urbano Suenia Vasconcelos Beltrão Isabel Cristina Lopes dos Santos Clarisse Martins Machado

The aim of this study was to characterize the urinary excretion of the BK (BKV) and JC (JCV) human polyomaviruses in a cohort of human immunodeficiency virus (HIV)-infected children and adolescents. One hundred and fifty-six patients were enrolled: Group I included 116 HIV-infected children and adolescents [median age = 11.4 years (y); range 1-22 y]; Group II included 40 non-HIV-infected health...

2014
Emilie Pambrun Catherine Mengelle Geneviève Fillola Patrick Laharrague Laure Esposito Isabelle Cardeau-Desangles Arnaud Del Bello Jacques Izopet Lionel Rostaing Nassim Kamar

The human polyomavirus BK (BKV) is associated with severe complications, such as ureteric stenosis and polyomavirus-associated nephropathy (PVAN), which often occur in kidney-transplant patients. However, it is unknown if BKV can replicate within bone marrow. The aim of this study was to search for BKV replication within the bone marrow of kidney-transplant patients presenting with a hematologi...

Journal: :Journal of clinical microbiology 2015
Morgane Solis Mariam Meddeb Charlotte Sueur Pilar Domingo-Calap Eric Soulier Angeline Chabaud Peggy Perrin Bruno Moulin Seiamak Bahram Françoise Stoll-Keller Sophie Caillard Heidi Barth Samira Fafi-Kremer

International guidelines define a BK virus (BKV) load of ≥4 log10 copies/ml as presumptive of BKV-associated nephropathy (BKVN) and a cutoff for therapeutic intervention. To investigate whether BKV DNA loads (BKVL) are comparable between laboratories, 2 panels of 15 and 8 clinical specimens (urine, whole blood, and plasma) harboring different BKV genotypes were distributed to 20 and 27 French h...

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2005
Patricia Muñoz Marta Fogeda Emilio Bouza Eduardo Verde Jesus Palomo Rafael Bañares

BACKGROUND BK virus (BKV) has been implicated as a cause of nephritis and graft loss in 2%-9% of kidney transplant recipients, but the prevalence among recipients of other solid organ transplants (SOTs) has not been well established. Our objective was to determine the prevalence of BKV infection for all types of SOT recipients at our medical center. METHODS A total of 156 consecutive SOT reci...

Journal: :The Journal of general virology 2000
A Dolei V Pietropaolo E Gomes C Di Taranto M Ziccheddu M A Spanu C Lavorino M Manca A M Degener

BK and JC polyomaviruses (BKV and JCV) are widespread in humans and are thought to persist and reactivate under immune alterations. In addition to the kidney, lymphoid cells have been proposed as a site of latency. However, while this was shown to occur in immunocompromised patients, discordant data were published for healthy humans. To help to solve this issue, an extensive study (231 healthy ...

Journal: :The Journal of infectious diseases 2009
Adrian Egli Laura Infanti Alexis Dumoulin Andreas Buser Jacqueline Samaridis Christine Stebler Rainer Gosert Hans H Hirsch

BACKGROUND The replication of BK virus (BKV) and JC virus (JCV) is linked to polyomavirus-associated nephropathy, hemorrhagic cystitis, and multifocal leukoencephalopathy in immunodeficient patients, but the behavior of these viruses in immunocompetent individuals has hardly been characterized. METHODS We used EIA to study samples obtained from 400 healthy blood donors aged 20-59 years for BK...

Journal: :The Journal of infectious diseases 2005
Parmjeet Randhawa Ron Shapiro Abhay Vats

BACKGROUND Renal allograft recipients can be monitored for polyomavirus-associated nephropathy (PVAN) using urine samples. Because virus in urine can be derived from the kidneys, ureter, or urinary bladder, we evaluated whether measurement of intrarenal concentrations of viral DNA might serve as a more reliable monitoring tool. METHODS Real-time quantitative polymerase chain reaction was used...

Journal: :American journal of clinical pathology 2005
Oyedele A Adeyi Dorothy R Belloni Scott D Dufresne Alan R Schned Gregory J Tsongalis

We used real-time polymerase chain reaction (PCR) technology to detect BK virus (BKV) in H and E-stained kidney biopsy sections, using laser capture microdissection. Renal allograft biopsy specimens from 4 patients with the histopathologic diagnosis of BKV-associated nephropathy (BKVAN; group 1) and 3 patients suspected to have BKVAN but without diagnostic histologic features (group 2) were ret...

Journal: :The new microbiologica 2007
Simona Marchetti Rosalia Graffeo Alessia Siddu Rosaria Santangelo Marco Ciotti Alessandra Picardi Cartesio Favalli Giovanni Fadda Paola Cattani

The BK polyomavirus (BKV) is widespread in the general population. In transplant recipients, the patients' weakened immune response may encourage reactivation of latent infection, leading to BKV-related diseases. Rapid and quantitative detection might help to delineate viral reactivation patterns and could thus play an important role in their clinical management. In our study we developed an "i...

Journal: :Antimicrobial agents and chemotherapy 2011
D Topalis I Lebeau M Krecmerová G Andrei R Snoeck

BK virus (BKV), a virus belonging to the polyomavirus family, is a circular double-stranded DNA virus that causes nephropathies in immunocompromised patients after kidney or bone marrow transplantation. The occurrence of polyomavirus-associated nephropathy in kidney transplant patients may trigger graft loss, and guidelines for the management of BKV infection have not yet been clearly establish...

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