نتایج جستجو برای: bk virus bkv

تعداد نتایج: 402180  

2010
Constantino Fernández Rivera Ángel Alonso Hernández Juan Mosquera Reboredo Ignacio Rodríguez Gómez

Viral infection has been related to post-transplantation tumour development, particularly Epstein-Barr virus, human papillomavirus, hepatitis B and C viruses, and herpes virus 8. Recently, BK virus (BKV) has emerged as an important cause of tumour formation in solid organ transplant recipients. BKV oncogenic potential relates to the ability to inactivate the functions of tumour suppression prot...

2012
Eva Girmanova Irena Brabcova Jiri Klema Petra Hribova Mariana Wohlfartova Jelena Skibova Ondrej Viklicky

BK polyomavirus infection is the important cause of virus-related nephropathy following kidney transplantation. BK virus reactivates in 30%-80% of kidney transplant recipients resulting in BK virus-related nephropathy in 1%-10% of cases. Currently, the molecular processes associated with asymptomatic infections in transplant patients infected with BK virus remain unclear. In this study we evalu...

2017
Nirupama Gupta Cuong Q. Nguyen Renee F. Modica Melissa E. Elder Eduardo H. Garin

BACKGROUND BK virus (BKV) is a ubiquitous polyoma virus that lies dormant in the genitourinary tract once acquired in early childhood. In states of cellular immunodeficiency, the virus can reactivate to cause hemorrhagic cystitis and nephritis. Children with systemic lupus erythematosus (SLE) have an increased risk of developing infectious complications secondary to their immunocompromised stat...

Journal: :Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003
Sylvia Stracke Udo Helmchen Lutz von Müller Donald Bunjes Frieder Keller

In 1971, two human polyoma viruses, BK and JC, were isolated and named after the patients in whom they were first identified [1]. BK virus (BKV) was isolated from the urine of a kidney transplant patient and JC virus (JCV) from the brain of a patient with Hodgkin’s lymphoma and progressive multifocal leukencephalopathy. Primary infection with these DNA viruses occurs early in childhood and 70–8...

Journal: :Clinical and vaccine immunology : CVI 2006
Parmjeet S Randhawa Gaurav Gupta Abhay Vats Ron Shapiro Raphael P Viscidi

Immunoglobulin G (IgG), IgA, and IgM antibodies were measured in serum samples from 71 organ donors, 81 kidney transplant recipients at transplantation, and 67 patients during the posttransplant period by using a virus-like particle-based enzyme-linked immunosorbent assay (ELISA). BK virus (BKV) and JC virus DNA were detected in urine and plasma by real-time PCR. IgG antibodies to BKV were demo...

Fereshte Ghandehari Mehrnaz Shanehsazzadeh Nahid Tajedin,

BK virus (BKV) is a polyomavirus with seroprevalence in adults, ranging from 60 to 100%. It is considered as usual cause of renal dysfunction after the allograft renal transplantation nephropathy. Potent immunosuppressive therapy in kidney transplantation can lower the rate of acute rejection. Therefore, untreated BKV infections lead to kidney allograft dysfunction or loss. In order to estimate...

2016
Robert Y. L. Wang Yi-Jung Li Wei-Chen Lee Hsin-Hsu Wu Chan-Yu Lin Cheng-Chia Lee Yung-Chang Chen Cheng-Chieh Hung Chih-Wei Yang Ya-Chung Tian

BK virus (BKV) is a polyomavirus that cause of allograft dysfunction among kidney transplant recipients. The role of BKV infection in non-renal solid organ transplant recipients is not well understood neither for the relationship between various BKV strains with occurrence of BKV viral viruria. This study aimed to understand the prevalence of BKV infection and identified of BKV various strains ...

2015
Nirupama Gupta Robert M. Lawrence Cuong Nguyen Renee F. Modica

BK virus (BKV) is a human polyomavirus with a seroprevalence of 60-80 % in the general population. In renal transplant patients, it is known to cause renal failure, ureteric stenosis and hemorrhagic cystitis. In bone marrow transplant patients, it is evident that BKV can also cause hemorrhagic cystitis along with BK virus nephropathy (BKVN) in the native kidneys, with subsequent renal failure. ...

Journal: :The Journal of infectious diseases 2005
Raymund R Razonable Robert A Brown Atul Humar Emma Covington Emma Alecock Carlos V Paya

In this study of 263 heart, kidney, liver, and pancreas transplant patients, BK virus (BKV) and JC virus (JCV) DNAemia were observed most commonly in kidney and/or pancreas transplant patients (26%), although they were also observed, to a lesser extent, in heart (7%) and liver (4%) transplant patients. The majority of episodes of polyomavirus DNAemia were subclinical, although, in some cases, B...

Journal: :Diyala Journal of Medicine 2022

Background: BK virus, a human polyomavirus, causes nephropathy and allograft loss in renal transplant recipients. Although it was discovered 1971, understanding of the humoral immune response to BKV is limited.
 Objective: To serological detection level estimation anti-BK-IgG renal-transplanted recipients healthy blood donors as control.
 Patients Methods: Serum samples were collected...

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