Perinatal exposure to nicotine imbalances the redox status in newborns. This study investigated effect of Anethum graveolens (dill) extract on oxidative stress and tissue injury liver kidney mice newborns exposed perinatally. Pregnant received (0.25 mg/kg) gestational day 12 5 after birth and/or A. 1 15 birth. Newborn showed multiple histopathological alterations liver, including inflammatory c...

OBJECTIVE Certain family structures have been identified as putting children at high risk for injury. To further define children at highest risk, we set out to explore the effect of an older sibling and birth interval on the risk of injury related hospital admission or death. METHODS Data were analyzed using a case-control design. Cases and controls were identified by linking longitudinal bir...

OBJECTIVE To study the relation between traumatic birth and the development of permanent facial palsy in the newborn. DESIGN Retrospective case control study of children with 'congenital' facial palsy. SETTING Two tertiary referral centres for patients with facial palsy. SUBJECTS 61 children with established facial palsy. MAIN OUTCOME MEASURES Odds ratios of recognised factors for birth...

UNLABELLED Survivors of preterm birth are at high risk of pervasive cognitive and learning impairments, suggesting disrupted early brain development. The limits of viability for preterm birth encompass the third trimester of pregnancy, a "precritical period" of activity-dependent development characterized by the onset of spontaneous and evoked patterned electrical activity that drives neuronal ...

Acute lung injury occurs mostly in the very low birth weight and extremely low birth weight infants. The pathological process leading to acute lung injury includes immature and/or diseased lung that experienced oxidative stress, inflammation and mechanical insult with the bronchial, alveolar and capillary injuries and cell death. It may be the first step to the subsequent development of chronic...

BACKGROUND Trauma occurs in 8% of all pregnancies. To date, no studies have evaluated the effect of the hospital's trauma designation level as it relates to birth outcomes for injured pregnant women. METHODS This population-based, retrospective cohort study evaluated the association between trauma designation levels and injured pregnancy birth outcomes. We linked Washington State Birth and Fe...

Over the course of decades, the incidence of brachial plexus birth injury (BPBI) has increased despite advances in healthcare which would seem to assist in decreasing the rate. The aim of this study is to identify previously unknown risk factors for BPBI and the risk factors with potential to guide preventative measures. A case control study of 52 mothers who had delivered a child with a BPBI i...