OBJECTIVES To compare Cloninger's dimensions of temperament and character in patients with bipolar I disorder (BP-I) and healthy controls from the general population. MATERIALS AND METHODS This cross sectional study included 96 BP-I patients (according to DSM-IV-TR criteria) that were admitted to a psychiatric hospital in Iran due to an acute episode of mania or depression, or a mixed episode...

abstract: introduction: psychiatric disorder is a disease in which patients suffer from emotional problems that these are visible in all aspect of patient’s life. studies show that there is a major difference between the prevalence of this disease in different countries and also show that this disorder is increasing. the aim of this study is to find the possible relationship between psychiatric...

INTRODUCTION The co-occurrence of attention deficit hyperactivity disorder (ADHD) in affective disorder patients is considerably high. The aims of the present study were to search for the frequency and impact of ADHD co-occurrence on the clinical features of affective disorders and to examine the relationship between the dominant affective temperaments and ADHD. METHODS In total, 100 patients...

Background Diagnostic biomarkers of major depressive disorder, bipolar disorder, and schizophrenia are urgently needed, because none are currently available. Methods We performed a comprehensive metabolome analysis of plasma samples from drug-free patients with major depressive disorder (n=9), bipolar disorder (n=6), schizophrenia (n=17), and matched healthy controls (n=19) (cohort 1) using l...

OBJECTIVE Personality dimension is considered as a risk factor of depression. This study was to compare aggression, impulsivity, hopelessness, and TCI (temperament and character dimensions) between patients with major depressive disorder (MDD) and normal controls. METHODS A total of 56 MDD patients and the same number of normal controls who were matched for age, gender, and education were rec...

OBJECTIVE Bipolar disorders are often not recognized and undertreated. The diagnosis of current or past episodes of hypomania is of importance in order to increase diagnostic certainty. The Hypomania Checklist-32 is a self-applied questionnaire aimed at recognizing these episodes. As part of the international collaborative effort to develop multi-lingual versions of the Hypomania Checklist-32, ...

objective: the aim of this study was to compare the qeeg of adolescents affected by bipolar ii disorder with age and gender matched healthy controls, and to extract the characteristics of the alpha frequency band to better understand this disorder. methods: twenty one adolescents affected by acute episodes of bipolar ii disorder (bmd ii), both hypomanic and depressive episodes, were selected vi...

BACKGROUND Bipolar disorder may be associated with a hypersensitive behavioral approach system and therefore to increased reward sensitivity. The objective of this study is to explore the interrelationships between bipolar disorder, behavioral addictions, and personality/temperament traits in a group of euthymic outpatients with bipolar I disorder and in a group of comparison subjects. METHOD...