Circadian rhythms maintain a high level of homeostasis through internal feed-forward and -backward regulation by core molecules. In this study, we report the highly unusual peripheral circadian rhythm of bone marrow mesenchymal stromal cells (BMSCs) induced by titanium-based biomaterials with complex surface modifications (Ti biomaterial) commonly used for dental and orthopedic implants. When c...

Bone marrow stimulation may be applied to regenerate focal cartilage defects, but generally results in transient clinical improvement and formation of fibrocartilage rather than hyaline cartilage. Tissue engineering and regenerative medicine strive to develop new solutions to regenerate hyaline cartilage tissue. This systematic review and meta-analysis provides a comprehensive overview of curre...

Keratins are naturally derived proteins that can be fabricated into several biomaterials morphologies including films, sponges and hydrogels. As a physical matrix, keratin biomaterials have several advantages of both natural and synthetic materials that are useful in tissue engineering and controlled released applications. Like other naturally derived protein biomaterials, such as collagen, ker...

Investigation of the mechanical behavior of biological tissues and biomaterials has been an active area of research for several decades. However, in recent years, the enthusiasm in understanding the mechanical behavior of biological tissues and biomaterials has increased significantly due to the development of novel biomaterials for new fields of application, along with the emergence of advance...

Recent advances in fields such as tissue engineering, advanced biomaterials and injectable polymers promise to alter the face of anterior segment surgery radically in coming years, according to an international panel of vision scientists. A clinical research symposium devoted to the theme of “New biomaterials and drug delivery in anterior segment surgery” enabled delegates attending the XXIII C...

Recent advances in additive manufacturing (AM) techniques (otherwise known as 3D printing) have enabled fabrication of a new class of porous biomaterials (Figure 1) with arbitrarily complex and precisely controlled topologies that e.g. resemble the geometry and micro-architecture of (trabecular) bone. Since the geometry of scaffolds and biomaterials is an important factor in bone tissue regener...

This Special Issue "Biodegradable Materials" features research and review papers concerning recent advances on the development, synthesis, testing and characterisation of biomaterials. These biomaterials, derived from natural and renewable sources, offer a potential alternative to existing non-biodegradable materials with application to the food and biomedical industries amongst many others. In...

T he study of peptideand protein-based biomaterials is of interest in itself because it probes and advances basic understanding of how natural biomaterials are constructed and used in biology. In addition, the successful development of new biomaterials presents new possibilities for applications in biotechnology and synthetic biology, such as templating inorganic materials that might lead to ne...

The rapid development of micro/nanoengineered functional biomaterials in the last two decades has empowered materials scientists and bioengineers to precisely control different aspects of the in vitro cell microenvironment. Following a philosophy of reductionism, many studies using synthetic functional biomaterials have revealed instructive roles of individual extracellular biophysical and bioc...

■ Abstract This review summarizes recent advances and future research trends in the field of phospholipid-based biomaterials. Lipids play an important role in biomineralization and countless other biological processes, and they are receiving increasing attention for the synthesis of new biomimetic biomaterials. Several emerging strategies in biomaterials research take advantage of phospholipids...