the disposed wastes of zinc industries contain large amounts of heavy metals such as pb2+ and cd2+. these elements are considered as hazardous elements to human beings and other organisms. this study aims at introducing the fungal isolates that evolved to be compatible with waste deposits during the time and can absorb pb2+ and cd2+ions. during the spring and autumn in 2011, eight samples of se...

celiac disease (cd) is now considered a multiple and systemic immune-mediate disorder triggered by the ingestion of wheat gluten and related proteins. following the discovery of a link between gluten and cd, it was demonstrated that gliadin, one of the two principal protein groups comprising gluten, plays a key role in cd. it has since become clear that the different and crucial roles of gliadi...

breast cancer (bc) accounts for one of the major health problems around the world. since the diagnosis process can have great effect on therapy outcomes, we studied the biomarkers specific to breast tumors stage i based on examining different iranian patients. cases from different stages were examined to discover their highly expressed proteins. in addition, pathologic evaluations were performe...

conclusions expression of armc3 in tumor samples and normal adjacent tissue is very important. the expression of this gene in tumor-adjacent tissue may be associated with the stage of cancer; it may be that these tissues are affected by epigenetic and oncogenic changes of breast cancer. accordingly, aberrant expression of armc3 in tumor samples may be an attractive candidate for use as a tumor ...

silver nanoparticles (agnps) have gained considerable interests during the last decade due to their excellent antimicrobial activities. despite their extensive use, the potential toxicity of these nanoparticles and possible mechanisms by which they may induce adverse reactions have not received sufficient attention and no specific biomarker exist to describe and quantify their toxic effects. na...

colorectal cancer remains one of the major cancer- related deaths despite progress in the treatment during past decades. detection of disease at earlier stages reduces its mortality. the aim of current study was to investigate expression of cytokeratin 19 (ck19), cytokeratin 20 (ck20) and guanylyl cyclase c (gcc) mrna in peripheral blood of non- metastatic colorectal cancer patients which may r...

surface oil seeps from alasht, lapur and jenesem share many compositional affinities including distributions and concentrations ofnormal alkanes, terpanes and steranes. these oils also show many similarities with that of jurassic sediments (shemshak group, klarizformation) systematically sampled from the galandrud coal mine. recent geochemical studies in this area indicated that theshemshak gro...

cancer incidence is projected to increase in the future and an effectual preventive strategy is required to face this challenge. alteration of dietary habits is potentially an effective approach for reducing cancer risk. assessment of biological effects of a specific food or bioactive component that is linked to cancer and prediction of individual susceptibility as a function of nutrient-nutrie...

polybrominated diphenyl ethers (pbdes) have been widely used in many products as flameretardants, which resulted in their release into the environment. little is known about the impact of coexisting pbdes on organisms. in this study, the in vivo effects of bde-47 and bde-99 on a suite of biomarkers, acetyl cholinesterase (ache), ethoxyresorufin-o-deethylase (erod), glutathione-s-transferase (gs...

surface oil seeps from alasht, lapur and jenesem share many compositional affinities including distributions and concentrations ofnormal alkanes, terpanes and steranes. these oils also show many similarities with that of jurassic sediments (shemshak group, klarizformation) systematically sampled from the galandrud coal mine. recent geochemical studies in this area indicated that theshemshak gro...