Journal:
:vaccine research
0
mohammad sadeq khosravy department of hepatitis and aids, pasteur institute of iran, tehran, iran, department of laboratory animal sciences, production and research complex, pasteur institute of iran, tehran, iran
mehdi shafiee ardestani department of radiopharmacy, faculty of pharmacy, tehran university of medical sciences, tehran, iran
reza ahangari cohan department of pilot biotechnology, pasteur institute of iran, tehran, iran
delaram doroud department of quality assurance, production and research complex, pasteur institute of iran, tehran, iran
safieh amini department of hepatitis and aids, pasteur institute of iran, tehran, iran
seyed bahman momen department of pilot biotechnology, pasteur institute of iran, tehran, iran
manufacturing new hepatitis b virus vaccines, specifically by the use of nanoparticles, is of high global interest. in this paper, a new biocompatible and biodegradable structure of nano-sized hepatitis b virus’ surface antigen (hbsag) was generated by conjugation with dendrimers, a low cost biodegradable and biocompatible polymer. the physicochemical properties of the conjugate were characteri...