Cancer is defined as a multifactorial disease because it exhibits the continuous proliferation of malignant cells. It one principal causes death worldwide, with breast cancer occurrence being highest among women and lung men. Hydroxyflavanones come under category flavonones are further classified 2′-hydroxyflavanone, 4′-hydroxyflavanone, 6-hydroxyflavanone, 7-hydroxyflavanone, etc. Flavonoids c...

The present study was designed to identify the DPPH (2, 2-diphenyl-1-picrylhydrazyl) free-radical scavenging constituents from methanol extract of L. nodiflora using bioassay-guided fractionation. The ethyl acetate fraction (EAF) revealed a strong antioxidant activity, compared to other fractions through in vitro DPPH radical-scavenging assay. The repeated fractionation of active EAF by silica ...

Antibiotics are metabolic by-products of complex biosynthetic pathways in microorganisms. They are usually produced by aerobic spore-forming bacteria in the genera Bacillus and Streptomyces and in the Fungi Penicillium and Cephalosporium. Antimicrobials such as bacteriocins are inhibitory peptides or proteins, which have bactericidal effects on micro-organisms closely related to the producer. T...

This work aimed at the development of biodegradable nanocapsules as carriers of two bioactive compounds, 5-aminosalycilic acid and glycomacropeptide. Nanocapsules were produced through layer-by-layer (LbL) deposition of chitosan (CH) and alginate (ALG) layers on polystyrene nanoparticles. The bioactive compounds were incorporated on the third layer of the nanocapsules being its encapsulation ef...

During the brewing process, lipid oxidation can lead to undesirable flavours in beer [I]. Naturally occuring phenols in malt (germinated barley) have proven their effectiveness as antioxidants [2]. Ferulic acid (4-hydroxy-3methoxy cinnamic acid) is the most abundant phenolic acid in barley. It acccounts for 0.14% of dry matter in barley grains 131, and it is mainly esterified to arabinofuranosy...

A new bioactive compound, namely desmodianone H(1), and another known compound uncinanone B(2) were first isolated using bioactivity-guided isolation from the leaves of Lespedeza maximowiczii and structures were elucidated by comprehensive analysis of their nuclear magnetic resonance and mass spectrometry data. Compounds 1 and 2 exhibited strong inhibitory effects on mushroom tyrosinase activity.

Cancer is one of the most severe illnesses afflicting mankind these days and certainly, the second one most lethal ailment after coronary heart ailment. There are various specific styles of cancer labeled with the aid of the type of cellular that is initially affected, and these consist of cervical most cancers, skin most cancers, leukemia, lung most cancers, liver cancer, breast cancer, prosta...