BACKGROUND Berberine is an isoquinoline alkaloid widely used to improve the glucidic and lipidic profiles of patients with hypercholesterolemia, metabolic syndrome, and type 2 diabetes. The limitation of berberine seems to be its poor oral bioavailability, which is affected by the presence, in enterocytes, of P-glycoprotein - an active adenosine triphosphate (ATP)-consuming efflux protein that ...

The life history of Puccinia striiformis remains a mystery because the alternate host has never been identified. Inoculation of grasses using aeciospores from naturally infected Berberis chinensis and B. koreana resulted in infection on Poa pratensis, producing uredinia typical of stripe rust caused by P. striiformis. Analyses using real-time polymerase chain reaction and DNA sequence confirmed...

Research on biochemical properties of Berberis vulgaris which has diverse usage areas has increased the popularity of this plant. In this study, antioxidant properties, organic acid contents and phenolic compound contents of Berberis vulgaris fruits naturally grown in Gevaş Region (Van Province/Turkey) were determined. With respect to organic acids, malic acid content was found as 1.862 g/kg, c...

Tests in vitro conditions with ethanol extracts from the radix of Berberis vulgaris and flower twig Tamarix tetrandra prepared by method maceration were performed two economically important plant pathogens such as Monilia laxa Phytophthora capsici. The received results show that common barberry (Berberis vulgaris) are able to fully block growth mycelium at 0.5 % (m/v) concentration during entir...

diabetes mellitus is a common endocrine disorder. anti-diabetic agents from natural and synthetic sources are available for the treatment of this disease. berberis integerrima is a medicinal shrub used in conventional therapy for a number of diseases. the aim of the present study was to investigate the effects of aqueous extract of berberis integerrima root (aebi) on some physiological paramete...

BACKGROUND Tissue protective effect of compounds with antioxidant properties has been demonstrated. The alkaloids found in barberry root are considered as antioxidants. OBJECTIVE According to barberry protective effects in different tissues, in this study, the protective effect of Berberis integerrima Bge. root )MEBIR) was evaluated against CCl4-induced testicular damages in Wistar rats. MA...

abstract seedless barberry (berberis vulgaris l. var. asperma) is one of the few crops that is cultured only in iran and southern parts of khorasan provinces. the origin of this variety is unknown and there has not been any study aiming to identify phylogenic relationships of this plant with other species existing in iran. in this study, aflp markers based on four primer combinations (ecori/tru...

A new steroid, itesmol 3-O-palmitate (1), along with two known steroids were isolated from the trunk of Berberis koreana. The structure of 1 was determined on the basis of spectroscopic analyses involving 2D NMR and chemical reactions. Compound 1 exhibited potential antiproliferative activity against A549, SK-OV-3, SK-MEL-2, and HCT-15 cell lines (respective IC(50) values of 7.41, 9.20, 4.53, a...

Berberis microphylla is a native plant that grows in Patagonia and is commonly used by aboriginal ethnic groups in traditional medicine as an antiseptic for different diseases. The present study evaluated the antibacterial and synergistic activity of alkaloid extracts of B. microphylla leaves, stems and roots used either individually or in combination with antibiotics against Gram-positive and ...