نتایج جستجو برای: benidipine

تعداد نتایج: 144  

Journal: :Molecular medicine reports 2012
Kohji Takara Mika Matsubara Kazuhiro Yamamoto Tetsuya Minegaki Shigehiko Takegami Minoru Takahashi Teruyoshi Yokoyama Katsuhiko Okumura

The effects of 9 calcium antagonists on ABCG2/BCRP-mediated resistance and transport were examined in HeLa and SN-38-resistant HeLa (HeLa/SN100) cells, overexpressing ABCG2/BCRP. Sensitivity to mitoxantrone, an ABCG2/BCRP substrate, in HeLa/SN100 cells was significantly reversed by the coexistence of the calcium antagonists, except for diltiazem a...

Journal: :Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 1995

Journal: :International Journal of Applied and Basic Medical Research 2017

2014
BAIXIANG WANG MING BI ZHEN ZHU LEI WU JINGYUN WANG

The dihydropyridine-type calcium channel blocker, benidipine (BD) has been widely used in hypertension therapy. Previous studies have demonstrated that BD has a positive effect on bone metabolism. Inspired by this promoting phenomenon, the present study investigated the effects of BD on osteoblasts in vitro. Experiments were designed and performed, including an MTT assay, reverse transcription-...

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