The interplay between bending of the molecule axis and appearance of disruptions in circular DNA molecules, with ∼100 base pairs, is addressed. Three minicircles with different radii and almost equal contents of AT and GC pairs are investigated. The DNA sequences are modeled by a mesoscopic Hamiltonian which describes the essential interactions in the helix at the level of the base pair and inc...

The determination of the appropriate boundary conditions for a two-dimensional theory of elastic flat plates (and shells) consistent with the expected order of accuracy of the theory is both critical and challenging. The reciprocal theorem of elasticity will be applied in a novel way to obtain the appropriate stress boundary conditions for plate bending accurate to all order (with respect to th...

In this paper, a displacement-based, variationally consistent, two variable refined theory for shear deformable beams is presented. The beam is assumed to be of linearly elastic, homogeneous, isotropic material and has a uniform rectangular cross-section. In this theory, the beam axial displacement and beam transverse displacement consist of bending components and shearing components. The assum...

Sharp bending of double-stranded DNA (dsDNA) plays an essential role in genome structure and function. However, the elastic limit of dsDNA bending remains controversial. Here, we measured the opening rates of small dsDNA loops with contour lengths ranging between 40 and 200 bp using single-molecule Fluorescence Resonance Energy Transfer. The relationship of loop lifetime to loop size revealed a...

ao"length of opening dh, dl"distance from top of steel section to centroid of concrete force at high and low moment ends of the opening, respectively dr"distance from outside edge of flange to centroid of reinforcement *b"maximum bending deflection for unperforated beam *m,b"maximum bending deflection for a member with an opening Fy"yield stress of steel FM y"reduced axial strength of steel in ...

Bending is one of the most common metal forming technology and it can be applied not only in sheet metal forming but also in forming of wires, rods, strips, pipes and bars. However, in car production, ship building and home appliance manufacturing sheet metal bending is most widely employed. One of the most significant sheet metal bending operations is V – Die bending. This process consists of ...

BACKGROUND Locking plates transmit load through fixed-angle locking screws instead of relying on plate-to-bone compression. Therefore, locking screws may induce higher stress at the screw-bone interface than that seen with conventional nonlocked plating. This study investigated whether locked plating in osteoporotic diaphyseal bone causes a greater periprosthetic fracture risk than conventional...

The effects of scale on the estimated stresses and safety factors in the humeri of several bird and bat species were investigated. This was accomplished by estimating the lift distribution across the wings at two extremes of flight, gliding flight and the downstroke in hovering, finding the center of lift on the wings at these two extremes and calculating the applied bending and twisting moment...

We numerically investigate deformations and modes of networks of semiflexible biopolymers as a function of crosslink coordination number z and strength of bending and stretching energies. In equilibrium filaments are under internal stress, and the networks exhibit shear rigidity below the Maxwell isostatic point. In contrast to two-dimensional networks, ours exhibit nonaffine bending-dominated ...