Fecal glucocorticoid metabolite (FGM) analysis is a non-invasive method to monitor animals' welfare in captivity and wild environments. Glucocorticoid also known as cortisol hormone that indicates the level of stress animals humans. This paper reviews use FGM on bears methodologies used study this every species bear. The review was descriptive review. were included are brown bear (Ursus arctos)...

All retinal disorders, regardless of their aetiology, involve the activation of oxidative stress and apoptosis pathways. The administration of neuroprotective factors is crucial in all phases of the pathology, even when vision has been completely lost. The retina is one of the most susceptible tissues to reactive oxygen species damage. On the other hand, proper development and functioning of th...

spillage of scoleces is a major problem in surgery of hydatid cysts, because each of them may develop into a new cyst if it settles on a suitable site such as the peritoneum. many surgeons believe that scoleces in ruptured hydatid cysts of the liver containing bile are not able to develop new cysts, because bile kills thein. in order to prove this idea, the viability of scoleces in such cysts w...

Intrahepatic cholangiocarcinoma (CCA) is a lethal malignancy of the biliary epithelium associated with p53 mutations, bile duct injury, inflammation, and fibrosis. Here, to validate these processes in CCA, we developed a liver cirrhosis model driven by chronic intermittent toxin exposure, which provokes bile duct injury/necrosis and proliferation, fibroblast recruitment, and progressive extrace...

Numerous attempts have been made clinically to differentiate between the various kinds of jaundice by means of the serum phosphatase determination (l-6). The conclusions drawn from such studies ar’e conflicting and leave one with no clear impression as to the merits of the test for the purpose mentioned above. In clinical studies in which neither autopsy nor operation is performed the correct d...

Intrahepatic cholangiocarcinoma (CCA) is a lethal malignancy of the biliary epithelium associated with p53 mutations, bile duct injury, inflammation, and fibrosis. Here, to validate these processes in CCA, we developed a liver cirrhosis model driven by chronic intermittent toxin exposure, which provokes bile duct injury/necrosis and proliferation, fibroblast recruitment, and progressive extrace...

hepatobiliary scintigraphy is a sensitive method for intra & extera hepatic bile leak diagnosis. bile lead may be seen after hepatobiliary surgery, trauma, inflammatory disease or malignant neoplasms. although sonography and ct scanning are useful for diagnosis of peritoneal or perihepatic fluid, they cannot prove bile ascites. hepatobiliary scintigraphy with tc-99m-ida agents is a physiolo...