background: salivary gland tumors form a major area in the field of oral pathology. b-cell lymphoma -2 (bcl-2) is an anti-apoptotic gene with up-regulation in various neoplasms. the aim of the present case-control study was to comparatively investigate the expression of bcl-2 protein in pleomorphic adenoma (pa) and mucoepidermoid carcinoma (mec) and assess its potential diagnostic role in diffe...

background: bcl-2 is the most important anti-apoptotic regulator and bax is a pro-apoptotic protein. the status of these parameters or the ration of bcl-2 to bax is important in malignant cell fate as well as normal cells. methods: sixty-two all patients and 62 healthy sex-and age-matched controls were studied. after genotyping, the promoter region of the bax and bcl-2 genes by rflp-pcr method ...

Textile waste water treatment for industrial reuse remains as a complicated problem due to several reasons. Among them are: 1) Higher levels of Biological Oxygen Demand (BOD), Chemical Oxygen Demand (COD) and Total Dissolved Solids (TDS) content of the waste water; 2) Non-biodegradable nature of organic dye stuffs present in the effluent. Thus, any adopted treatment system, especially with resp...

The apicomplexan Toxoplasma gondii (Nicolle et Manceaux, 1908) secretes a group of serine/threonine kinases from rhoptries, which play vital roles in boosting intracellular infection. rhoptry organelle protein 17 (ROP17) is one these important kinase proteins. Nevertheless, its function remains unclear. Here, we showed that ROP17 induced autophagy vitro and vivo. small intestine tissues T. tach...

background : biomarkers accepted for clinical use in breast cancer have low sensitivity and specificity. thus, there is a need for new markers to assist in the diagnosis, prognosis and follow-up of breast cancer patients. this study aims to investigate the diagnostic, prognostic and follow-up role of serum bcl-2, bax and p53 proteins in breast cancer patients in comparison with those of serum c...

Introduction Background: Considering the poorly understood mechanism of lysine demethylase 1A (KDM1A) in osteosarcoma (OS), we here commence our investigation to fill blank. Material and methods Methods: Following transfection as appropriate, 3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) flow cytometry assays were used determine viability apoptosis OS cells MG-63, which ge...

Other names: BAM, BIM, BIM-alpha6, BIM-beta6, BIM-beta7, BOD, BimEL, BimL HGNC (Hugo): BCL2L11 Location: 2q13 Local order: According to GeneLoc and NCBI Map Viewer, genes flanking BCL2L11 in plus strand direction are: ACOXL 2q13 (acyl-Coenzyme A oxidase-like); PAFAH1P2 2q13 (platelet-activating factor acetylhydrolase, isoform Ib, pseudogene 2). Note: BCL2L11/BIM is a BH3-only protein from the B...