Abstract Background and Aims: For more than half a century, the production of fowl pox vaccine at Razi Vaccine and Serum Research Institute, has been carried out by injection method in the chick chorioallantoic membrane (CAM) and the vaccine has a favorable and effective in poultry flocks and has provided a complete satisfaction to the poultry flocks owner. Fowl pox vaccine is also manufactured...

Mycoplasma agalactia was cultured in PPLO broth medium supplemented with sterilized normal horse serum in fermentor. Cultivation process continued at 37 ºC under aerobic conditions and growth was terminated after 26 hours cultured period with 2.2×109 Mycoplasma per ml. Samples were taken at different stages of growth. Culture was inactivated with 0.04 %v/v formaldehyde and the vaccine was adjuv...

introduction: epidermal growth factor receptor (egfr) has been shown to play a critical role in tumor cell growth and its overexpression has been observed in many epithelial tumors. in the field of cancer vaccine research, displaying the peptide mimotope on the surface of phage particles has shown promising results. methods: in this study using m13-pviii phage display system, two constructs wer...

Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...

Human Papilloma Virus (HPV) vaccine recently has been added to the Iran Drug List, decision makers need information beyond that available from RCTs to recommend funding for this vaccination program to add it to the National Immunization program in Iran. Modeling and economic studies have addressed some of those information needs in foreign countries. In order to determine the long term benefit ...

infectious bronchitis (ib) is an economically important disease of chickens. due to the emergence of new variants of infectious bronchitis virus (ibv), the control of ib has become a serious problem for the poultry industry worldwide. in the present study, the nucleocapsid gene (n) and 3' untranslated region (utr) of two ibvs isolated from iranian poultry farms were sequenced and compared with ...

Background: Recent studies indicate an increased incidence of pertussis disease in recent years. The aim of this study was to evaluate the efficacy of the acellular vaccine for children (as a replacement of current whole cell vaccine in the Expanded Program on Immunization) and for high-risk adults in Iran through updating current best available evidence.   Methods: We performed a syste...

Foot-and-mouth disease is an important viral disease of cloven-hoofed animals. Inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. The choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. Montanide ISA 61 VG is a new ready-to-use mineral oil-based adjuvant developed by SEPPIC Inc....

background and aims: influenza vaccination is one of the best way to prevent and control influenza worldwide. it is manufactured by who-licensed companies based on the who expertise committee annually. the aim of this study was partial quality control of the commercial human influenza vaccine 2008-9 and its matching with the circulating strains. materials and methods: the trivalent imported vac...