Traumatic basal ganglia hematoma is a rare condition defined as presence of hemorrhagic lesions in basal ganglia or adjacent structures suchas internal capsule, putamen and thalamus. Bilateral basal ganglia hematoma are among the devastating and rare condition. We herein report a 28-year old man, a victim of car-car accident who was brought to our surgical emergency room by immediate loss of co...

Although a number of studies suggest an association between stroke and depression, few have examined the relation between magnetic resonance imaging (MRI)-identified lesions and depression among community-dwelling older adults. This cross-sectional study sought to assess the association between MRI infarcts in the basal ganglia and non-basal-ganglia areas, potential functional consequences of t...

Biotin-thiamine-responsive basal ganglia disease is a devastating autosomal recessive inherited neurological disorder. We conducted a retrospective chart review of all patients with biotin-thiamine-responsive basal ganglia disease who underwent a formal psychological assessment. Six females and 3 males were included. Five patients (56%) had an average IQ, two patients (22%) had mild delay, and ...

Movement disorders are primarily associated with the basal ganglia and the thalamus; therefore, movement disorders are more frequently manifest after stroke compared with neurological injuries associated with other structures of the brain. Overall clinical features, such as types of movement disorder, the time of onset and prognosis, are similar with movement disorders after stroke in other str...

The basal ganglia, said Kinnear-Wilson in the 1920s, have all the clarity of a dark basement. And so it has remained for the better part of a century. There are now major new ideas about what these deeplying structures in the forebrain may be doing. Lesions of the basal ganglia lead to devastating motor disorders, including Parkinson’s disease and Huntington’s disease. In addition, the basal ga...

In this study, we focused on the gait of Parkinson’s disease (PD) and presented a gray box model for it. We tried to present a model for basal ganglia structure in order to generate stride time interval signal in model output for healthy and PD states. Because of feedback role of dopamine neurotransmitter in basal ganglia, this part is modelled by “Elman Network”, which is a neural network stru...

introduction: huntington disease (hd) is a progressive neurodegenerative disease which affects movement control system of the brain. hd symptoms lead to patient’s gait change and influence stride time intervals. in this study, we present a grey box mathematical model to simulate hddisorders. this model contains main physiological findings about bg. methods: we used artificial neural networks (a...