BACKGROUND We previously identified a MUC5B gene promoter-variant that is a risk allele for sporadic and familial Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia (IPF/UIP). This allele was strongly associated with increased MUC5B gene expression in lung tissue from unaffected subjects. Despite the strong association of this airway epithelial marker with disease, little is known of mu...

Airway multiciliated epithelial cells play crucial roles in the mucosal defense system, but their differentiation process remains poorly understood. Mice lacking the basal body component Chibby (Cby) exhibit impaired mucociliary transport caused by defective ciliogenesis, resulting in chronic airway infection. In this paper, using primary cultures of mouse tracheal epithelial cells, we show tha...

The En/Spm transposable element system in maize includes the functional element, En/Spm and the receptor element I/dSpm. An En receptor has been found that shows En-induced breakage. This En-responsive receptor (designated I836518) is located on the short arm of chromosome 9, proximal to Wx. In the presence of En, markers distal to the receptor show a loss of gene expression. Kernels heterozygo...

objective(s) ziziphora clinopodioides lam. is a plant widely used in iranian traditional medicine for gastrointestinal disorders. several reports have demonstrated antibacterial (helicobacteria pylori), antioxidant and anti­inflammatory properties of z. clinopodioides. the aim of this study was to investigate the effects of aqueous- ethanol extract of z. clinopodioides on rat’s gastric acid out...

Anderson (3) has recently developed a pleasing reconstruction of the basal body from primate oviducts. A reexamination of some of the details, however, suggests a few modifications . The present writer finds the following four points open to doubt: (a) the tubules constituting the nine triplets are helical in a left-handed sense ; (b) the tubules make an angle of 10 °-15° with the axis of the b...

The effect of the cholinergic agonist carbachol (CCh) on backpropagating action potential (bAP)-evoked Ca transients in distal apical and basal dendrites of layer 2/3 pyramidal neurons in the primary visual cortex of rats was studied using whole-cell recordings and confocal Ca imaging. In the presence of CCh (20 μM), initial bAP-evoked Ca transients were followed by large propagating secondary ...

In Trifolium repens removal of any number of existing branches distal to a nodal root stimulates development of axillary buds further along the stem such that the complement of branches distal to a nodal root remains constant. This study aimed to assess possible mechanisms by which existing branches correlatively inhibit the outgrowth of axillary buds distal to them. Treatments were applied to ...

Objective(s) Ziziphora clinopodioides Lam. is a plant widely used in Iranian traditional medicine for gastrointestinal disorders. Several reports have demonstrated antibacterial (Helicobacteria pylori), antioxidant and anti‌inflammatory properties of Z. clinopodioides. The aim of this study was to investigate the effects of aqueous- ethanol extract of Z. clinopodioides on rat’s gastric acid ou...

after harvesting, pistachio nuts are generally kept in storage before being exported. during handling, thenuts are exposed to external forces that cause mechanical damage to them. the increase of the mechanicaldamage is a function of storage conditions, especially temperature. this research investigated the effect ofstorage temperature (25, 5, -5, -15°c), on the mechanical properties of pistach...