β-barrel membrane proteins are composed of multiple antiparallel β-strands and form pores in the outer membranes of endosymbiotic organelles like mitochondria and the evolutionary related Gramnegative bacteria. These β-barrel channels are crucial for signal transduction, metabolite transport, and protein translocation. How are β-barrel membrane proteins assembled into the outer membrane? After ...

The aim of this study was to increase understanding of the mechanism and dominant drivers influencing phase separation during ram extrusion of calcium phosphate (CaP) paste for orthopaedic applications. The liquid content of extrudate was determined, and the flow of liquid and powder phases within the syringe barrel during extrusion were observed, subject to various extrusion parameters. Increa...

Experimental evidence from mutant or genetically altered mice indicates that the formation of barrels and the proper maturation of thalamocortical (TC) synapses in the primary somatosensory (barrel) cortex depend on mechanisms mediated by neural activity. Type 1 adenylyl cyclase (AC1), which catalyzes the formation of cAMP, is stimulated by increases in intracellular Ca(2+) levels in an activit...

background: the rodent somatosensory barrel cortex is an ideal model to examine the effect of experience-dependent plasticity on developing brain circuitry. sensory deprivation such as whisker deprivation may affect neuroanatomical aspects of the brain during developmental processes. the present study designed to investigate the possible effects of whisker deprivation on the morphometric charac...

Birth-enucleated rodents display enlarged representations of whiskers (i.e., barrels of the posteromedial subfield) in the primary somatosensory cortex. Although the historical view maintains that barrel expansion is due to incremental increases in neuronal activity along the trigeminal pathway during postnatal development, recent evidence obtained in experimental models of intramodal plasticit...

Two advanced processes have been developed for fabricating ultra thick and ultra high aspect ratio (HAR) microstructures. One is the SU-8 based deep x-ray lithography (SU-8 based DXRL) process which uses the normal deep x-ray beam to expose the negative SU-8 resist. Another one is wave length shifter(WLS) based Ultra deep x-ray lithography (WLS-UDXRL) process which uses special ultra deep x-ray...

سلج 36 روم 07 / 02 / 94 و يس و دصكي نيمشش يشهوژپ ياروش هسلج تروص 1 . هسلج ليكشت تعاس و خيرات ،زور : زور هبنشود خيرات هب 07 / 02 / 94 هسلج نامز تدم 2 زا تعاس 14 تياغل 16 2 . يدعب هسلج خيرات : 28 / 02 / 94 3 . هسلج ليكشت لحم : يشهوژپ تنواعم رتفد 4 . هسلج رد هدننك تكرش ءاضعا : 1 ناراجشا يلع رتكد 2 رتكد يمولظم يلع رف 3 رفدنمجرا سابع رتكد 4 يرفعج دمحم رتكد يدنره 5 يضاق ديعس رتكد يبرغم ...

The barrel field of the somatosensory cortex constitutes a well documented example of anatomofunctional compartmentalization and activity-dependent interaction between neurons and astrocytes. In astrocytes, intercellular communication through gap junction channels composed by connexin 43 and 30 underlies a network organization. Immunohistochemical and electrophysiological experiments were under...

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We report on the study of the eeect of the Tile calorimeter thickness in the ATLAS Barrel calorimeter performance. The reduction of the Tile Calorimeter depth by 20 cm would have severe consequences on the hadron calorimeter performance and would increase the punchtrough probability in the muon chambers placed behind the calorimeter. Cost savings are also analysed.