Herpesviruses are main sculptors of natural killer (NK) cell repertoires. While the ?-herpesvirus human cytomegalovirus (CMV) drives accumulation adaptive NKG2C-positive NK cells, ?-herpesvirus Epstein–Barr virus (EBV) expands early differentiated NKG2A-positive cells. cells support immunity by antibody-dependent cellular cytotoxicity, seem to preferentially target lytic EBV replicating B The i...

Background: Immunophenotyping in the rare group of nodal Peripheral T-cell Lymphomas (PTCL) exposes interesting features such as T-cell marker downregulation and paradoxically, the presence of reactive, clustered large-sized CD20 positive B-cells (B-cell proliferation). Epstein-Barr virus (EBV) has been suggested as a putative etiology in pathogenesis of B-cell lymphoma. We aimed to review the ...

Background Epstein-Barr virus (EBV) infects almost a large percent of the world’s adult population. Antibody prevalence rates reach 95% or higher among elderly individuals. Even in the pediatric population, Epstein Barr infection is common. Young children most likely acquire primary EBV infection from close contact that involves exchange of oral secretions via shared items such as toys, bottles...

As the first discovered human cancer virus, Epstein-Barr virus (EBV) causes Burkitt's lymphoma and nasopharyngeal carcinoma. Isolating virions for determining high-resolution structures has been hindered by latency—a hallmark of EBV infection—and atomic are thus available only recombinantly expressed proteins. in present study, symmetry relaxation subparticle reconstruction, we have determined ...

Hemophagocytic lymphohistiocytosis (HLH) is a rare, potentially lethal condition due to dysfunctional immune response causing severe inflammatory syndrome. Epstein-Barr virus (EBV) – induced HLH form of secondary HLH, very serious presentation an otherwise benign viral infection. Here we present case 31 year old previously healthy male with prolonged fever and constitutional symptoms, eventuall...

Epstein–Barr virus (EBV) is the prototypic human tumor whose continuous lifelong immune control required to prevent lymphomagenesis in more than 90% of adult population that are healthy carriers virus. Here, we review recent evidence this has not only target latent oncogenes, but also lytic replication EBV. Furthermore, genetic variations identify molecular machinery cytotoxic lymphocytes as es...

abstract   background: nasopharyngeal carcinoma (npc) is a nonlymphomatous squamous cell carcinoma (scc) that occurs in the epithelial lining of the nasopharynx. viral, geographic, and ethnic factors are responsible for its multifactorial futures. previous studies have showed the role of epstein-barr virus (ebv) in the pathogenesis of npc but no study has been conducted on the iranian populatio...

Kanker nasofaring (KNF) merupakan kanker yang berasal dari sel epitel berada di rongga belakang hidung dan langit-langit mulut. Karsinoma sangat erat kaitannya dengan infeksi Epstein Barr Virus (EBV). Pengobatan dapat ditempuh memlaui berbagai cara, seperti operasi atau pembedahan, radioterapi, kemoterapi, terapi hormon, imunoterapi. Pada makalah ini disusun model matematika perkembangan akibat...