PURPOSE To report the efficacy of povidone-iodine as a treatment for conjunctivitis in pediatric patients. DESIGN Double-masked, controlled, prospective clinical trial. METHODS In an ophthalmology clinic in a general hospital in Manila, Philippines, 459 children (mean [SD] age 6.6 [6.6] years; range, 7 months-21 years) with acute conjunctivitis were studied. Infected eyes were cultured for ...

C onjunctiva is a thin, translucent membrane lining the anterior part of the sclera and inside of the eyelids. It has 2 parts, bulbar and palpebral. The bulbar portion begins at the edge of the cornea and covers the visible part of the sclera; the palpebral part lines the inside of the eyelids (Figure 1). Inflammation or infection of the conjunctiva is known as conjunctivitis and is characteriz...

Fusidic acid 1% and chloramphenicol 0.5% eye drops were in a randomized, single-blind manner given as a one-week treatment to out-patients with acute, purulent conjunctivitis. A clinical success was recorded in 84% (102/121) of patients receiving fusidic acid and in 81% (104/129) of patients receiving chloramphenicol. More patients (14%) receiving chloramphenicol complained of trivial side effe...

The tear lysozyme content in 111 normal subjects and in 159 patients with various conjunctival diseases was determined by a single radial immunodiffusion technique. Tear lysozyme level in normal people was 1.33/mg/ml. (SI conversion: mg/ml = g/l.) The mean tear lysozyme levels in patients with chronic irritative conjunctivitis (0.97 mg/ml) and nutritional deficiency with epithelial xerosis (0.7...

PURPOSE Bacterial eye infections are commonly treated with topical antibiotics, despite limited evidence of effectiveness. Azithromycin 1% in DuraSite((R)) is a new formulation of azithromycin in a gel polymer designed for use in acute bacterial conjunctivitis. METHODS We conducted systematic searches of the Cochrane Database of Clinical Trials, PubMed and Google Scholar to find randomized co...

BACKGROUND The purpose of this study was to determine the efficacy of besifloxacin ophthalmic suspension 0.6% when used in the treatment of bacterial conjunctivitis infections due to Pseudomonas aeruginosa. METHODS We undertook a post hoc analysis of clinical outcomes in patients with bacterial conjunctivitis due to P. aeruginosa across four prospective, multicenter, double-masked, randomized...

NEW DRUGS Eyedrops for Bacterial Conjunctivitis The FDA has approved besifloxacin ophthalmic suspension 0.6% (Besivance, Bausch & Lomb), a topical eyedrop for patients with nonviral bacterial conjunctivitis. Bacterial forms of conjunctivitis are common in childhood, but they can occur in people of any age. Symptoms can include reddened eyes, swelling, eyelids sticking together, itching, waterin...