نتایج جستجو برای: b thalassemia

تعداد نتایج: 917848  

Journal: :The Southeast Asian journal of tropical medicine and public health 2013
Rattika Saetung Siriwan Ongchai Pimlak Charoenkwan Torpong Sanguansermsri

Beta thalassemia is a common hereditary hemalogogical disease in Thailand, with a prevalence of 5-8%. In this study, we evaluated the high resolution DNA melting (HRM) assay to identify beta thalassemia mutation in samples from 143 carriers of the beta thalassemia traits in at risk couples. The DNA was isolated from venous blood samples and tested for mutation under a series of 5 PCR-HRM (A, B,...

Journal: :گوارش 0
fatemeh mirershadi alireza jafari masoud ghane

background: generally, a number of people with î²-thalassemia are susceptible to hbv since they receive multiple blood transfusions. these people have high infection rates despite vaccination against hbv. in this study, we explore the seroprevalence and risk factors of hbv infection in thalassemic patients who reside in ardabil. materials and methods: hospital in ardabil. patients' demographic ...

2006
Dimitrios I. Zafeiriou Marina Economou Miranta Athanasiou-Metaxa

Over the years, several reports have demonstrated involvement of the nervous system in b-thalassemia patients. Neurological complications have been attributed to various factors such as chronic hypoxia, bone marrow expansion, iron overload, and desferrioxamine neurotoxicity. In most cases, neurological involvement does not initially present with relevant signs or symptoms (i.e., is subclinical)...

Journal: :iranian journal of medical sciences 0
h. karamifar m. shahriari gh. amirhakimi

background: b-thalassemia major is a serious medical problem. growth retardation is commonly seen in poly-transfused b- thalassemia patients. the exact mechanism of short stature in children with thalassemia major is not well understood, however, it is believed to be multi-factorial. objective: to study the growth state and its relationship to growth hormone (gh) deficiency in b-thalassemia pat...

2015
Amin Abolhasani Foroughi Hosein Ghaffari Sezaneh Haghpanah Masoume Nazeri Roghieh Ghaffari Marzieh Bardestani Mehran Karimi

BACKGROUND In patients with thalassemia, chronic anemia causes bone marrow expansion and consequently skeletal manifestation in spine, skull, face and rib bones. OBJECTIVES We aimed to compare chest radiographic findings and facial bone deformity in patients with thalassemia major (TM) and intermedia. PATIENTS AND METHODS In this cross sectional study, 86 consecutive thalassemia patients re...

Journal: :iranian journal of immunology 0
ali asghar vahidi department of pediatrics and neonatology majid varesvazirian department of pediatrics and neonatology ayeh shamsadini department of pediatrics and neonatology sadollah shamsadini department of dermatology, school of medicine, kerman university of medical sciences, kerman, iran

background: thalassemia patients are more susceptible to hepatitis than the normal population due to the frequent blood transfusions. objective: to determine the immune response of children with major ß-thalassemia, by measuring anti-hepatitis b surface antibody (anti-hbs ab) following the last hbv vaccine injection. methods: this study was carried out on 215 thalassemic children who received t...

Journal: :Turkish journal of haematology : official journal of Turkish Society of Haematology 2011
Sunita Sharma Sonal Jain Malhotra Richa Chauhan

Coinheritance of hereditary spherocytosis (HS) and b thalassemia is very rare. HS is a familial haemolytic disorder resulting from primary abnormality of red cell membrane. It is transmitted as an autosomal dominant trait. b thalassemia is also a common inherited disorder. In Indians, the frequency of b thalassemia is reported between 3.5&14.9% [1]. The haemolytic anemia resulting from their co...

2015
Maryam Jafroodi Ali Davoudi-Kiakalayeh Zahra Mohtasham-Amiri Ali Akbar Pourfathollah Azade Haghbin

BACKGROUND Hepatitis C virus (HCV) is the leading cause of transfusion transmitted infections (TTIs) among patients with β-thalassemia major. A high prevalence of HCV was reported among these patients. The aim of this study is seeking the trend of the prevalence of HCV infection among the patients with b-thalassemia major in Guilan province, Northern Iran over a 10-year period. METHODS A retr...

2003
Turker Cetin Oguzhan Yildiz Ismail H. Kocar

Background: Persons with -thalassemia minor usually are symptomless. However, we previously reported renal ubular dysfunction in a patient with -thalassemia minor. The aim of this study is to investigate renal function in atients with -thalassemia minor. Methods: Forty-one subjects with -thalassemia minor and 20 sexand ge-matched healthy subjects were enrolled in the study. For analysis, patien...

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