nancy by the developing embryo after conception and later by the syncytiotrophoblast to prevent disintegration of the corpus luteum of the ovary. hCG also plays a role in cellular differentiation/proliferation and may activate apoptosis (1). hCG is extensively used as a parenteral fertility medication in lieu of luteinizing hormone. hCG is composed of 244 amino acids with a molecular mass of 36...

BACKGROUND Several studies have indicated that cryptorchidism is associated with degenerative changes in both Sertoli cells and germ cells. The gonadal peptide hormone inhibin B reflects Sertoli cell function. Low inhibin B levels are found in a large portion of formerly cryptorchid men who show compromised seminiferous tubule function. It is not known if inhibin B can be used to demonstrate ea...

BACKGROUND Solitary fibrous tumors are rare tumors of mesenchymal origins, most commonly seen arising from the pleural lining of the lungs. These are generally benign tumors, which in rare cases have been identified to be associated with multiple para-neoplastic syndromes. CASE REPORT This is a case of a solitary fibrous tumor of the pleura in a 49 year old female which was found to be associ...

Methotrexate (MTX) is an accepted regimen for conservative treatment of unruptured ectopic pregnancy. However ,gestational sac greater than 3.5 cm, existence of cardiac activity and high titers of serum beta human chorionic gonadotrophin ( B-HCG) levels are relative contraindications of Mtx treatment. A 29-year-old, gravida 3, parity 1 and a 34-year-old nulliparous women presented with a compla...

We recently showed that endometrial tissue produces hCG during the secretory phase of the menstrual cycle. Based on these findings, we hypothesized that the decidua should also be able to secrete hCG. We examined the decidualized endometrium of patients with extrauterine pregnancies. Decidual specimens were obtained for mRNA extraction and paraffin embedding from 24 patients that were between w...

Background: Patients with ectopic pregnancy and low serum β-HCG concentrations are commonly treated systemic methotrexate. Aim: To compare the outcome of methotrexate versus expectant management for females presenting pregnancy. Study design: Randomized controlled trial. Methodology: Females (n=140) were enrolled in study. Blood sample was taken beta-HCG noted. Then randomly divided two groups ...

Testosterone is produced in male rats by the action of luteinizing hormone (LH), an anterior pituitary hormone which interacts with receptors on Leydig cells (testes) to activate adenylate cyclase. A most frequently used agonist for LH is human chorionic gonadotropin (hCG), a hormone synthesized by the placenta during the early stages of pregnancy. Like LH, it is a heterodimer consisting of two...