Recent advances in data intensive computing for science discovery are fueling a dramatic growth in the use of dataintensive iterative computations. The utility computing model introduced by cloud computing, combined with the rich set of cloud infrastructure and storage services, offers a very attractive environment in which scientists can perform data analytics. The challenges to large-scale di...

Recent advances in data intensive computing for science discovery are fueling a dramatic growth in use of data-intensive iterative computations. The utility computing model introduced by cloud computing combined with the rich set of cloud infrastructure and storage services offers a very attractive environment for scientists to perform data analytics. The challenges to large-scale distributed c...

Joint genetic and neuroimaging data analysis on large cohorts of subjects is a new approach used to assess and understand the variability that exists between individuals. This approach has remained poorly understood so far and brings forward very significant challenges, as progress in this field can open pioneering directions in biology and medicine. As both neuroimagingand genetic-domain obser...

Results Examples will be given in a number of diseases but focusing on breast cancer and the results from the AZURE trial on the use of zoledronic acid, as well as from CALGBB trial 9741 which evaluated a dose-dense treatment strategy, as proposed by Norton and Simon. Results will be presented, including quantification of the cellkilling effect of zoledronic acid from the AZURE trial, which dem...

Azure DocumentDB is Microsoft’s multi-tenant distributed database service for managing JSON documents at Internet scale. DocumentDB is now generally available to Azure developers. In this paper, we describe the DocumentDB indexing subsystem. DocumentDB indexing enables automatic indexing of documents without requiring a schema or secondary indices. Uniquely, DocumentDB provides real-time consis...

Biodegradation of Orange II, Tropaeolin O, Congo Red, and Azure B in cultures of the white rot fungus, Phanerochaete chrysosporium, was demonstrated by decolarization of the culture medium, the extent of which was determined by monitoring the decrease in absorbance at or near the wavelength maximum for each dye. Metabolite formation was also monitored. Decolorization of these dyes was most exte...

Cloud computing has emerged as one of the preferred platforms for on-demand, event-driven computing. However, literature on event-driven scientific modeling on the cloud is sparse. This paper presents our vision and architecture to provide a “Scientific Modeling as a Service”in an on-demand fashion. We choose one of the most widely used groundwater models, MODFLOW2000, from USGS to develop a Mo...