نتایج جستجو برای: azelnidipine
تعداد نتایج: 144 فیلتر نتایج به سال:
A growing body of evidence indicates that renal tissue injuries are reversible. We investigated whether dietary salt reduction with the combination therapy of angiotensin II type 1 receptor blocker (ARB) plus calcium channel blocker (CCB) reverses renal tissue injury in Dahl salt-sensitive (DSS) hypertensive rats. DSS rats were fed a high-salt diet (HS; 4% NaCl) for 4 weeks. Then, DSS rats were...
UNLABELLED Aims/Introduction: Angiotensin II type 1 receptor blockers (ARB) are regarded as first-line treatment for type 2 diabetes with hypertension. However, lowering blood pressure to the target level often requires more than one antihypertensive agent as recommended by the guideline. In this open-label, prospective, crossover clinical trial, we compared the effects of combination treatmen...
A simple, specific, accurate and precise spectrophotometric method was developed validated for simultaneous estimation of Azelnidipine Valsartan in Synthetic Mixture. The wavelength 240.00 nm 250.00 nm. Beer’s law is obeyed the concentration range 2-10μg/ml 16-80μg/ml correlation coefficient 0.9999 0.9993 respectively. % recovery were found to be 101.2 - 101.9 101.8 Intraday precision 0.06 – 0....
To assess whether azelnidipine (AZN) exerts renoprotective effects, 20-week-old adult male stroke-prone spontaneously hypertensive rats (SHRsp) were treated with AZN 10 mg/kg/d (n=6), olmesartan (OLM) 3 mg/kg/d (n=4), hydralazine (HYD) 20 mg/kg/d (n=3), or water (control; n=5). Each test agent was administered by oral gavage for 12 weeks. Systolic blood pressure (SBP) was measured every 2 weeks...
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