Center for Evolutionary Functional Genomics, The Biodesign Institute, Arizona State University, Tempe, AZ 85287-5301 School of Life Sciences, Arizona State University, Tempe, AZ 85287-4501 Department of Electrical Engineering, Ira A. Fulton School of Engineering, Arizona State University, Tempe AZ 85287-5706 Department of Computer Science and Engineering, Ira A. Fulton School of Engineering, Ar...

Ornithine decarboxylase (ODC) is the most notable example of a protein degraded by the 26 S proteasome without ubiquitination. Instead, ODC is targeted to degradation by direct binding to a polyamine-induced protein termed antizyme (Az). Antizyme inhibitor (AzI) is an ODC-related protein that does not retain enzymatic activity yet binds Az with higher affinity than ODC. We show here that like O...

Associated Infections Sierra Simmons, MD; Shimon Kusne, MD; Holenarasipur R. Vikram, MD, FACP, FIDSA; Qing Wu, ScD; Ann Marie Roy-Hughes, RN; Janis Blair, MD; Internal Medicine, Mayo Clinic Arizona, Phoenix, AZ; Division of Infectious Diseases, Mayo Clinic Hospital, Phoenix, AZ; Research Biostatistics, Mayo Clinic Arizona, Scottsdale, AZ; Practice and Planning Analysis, Mayo Clinic Arizona, Pho...

Cassava (Manihot esculenta Crantz) plant resists water-deficit stress by shedding leaves leading to adaptive water-deficit condition. Transcriptomic, physiological, cellular, molecular, metabolic, and transgenic methods were used to study the mechanism of cassava abscission zone (AZ) cell separation under water-deficit stress. Microscopic observation indicated that AZ cell separation initiated ...

BACKGROUND The prostatic anterior zone (AZ) is not targeted routinely by TRUS guided prostate biopsy (TRUS-Pbx). MRI is an accurate diagnostic tool for AZ tumors, but is often unavailable due to cost or system restrictions. We examined the diagnostic yield of office based AZ TRUS-Pbx. METHODS 127 men at risk for AZ tumors were studied: Patients with elevated PSA and previous extended negative...

ODC (ornithine decarboxylase), the first enzyme in the polyamine biosynthesis pathway in mammalian cells, is a labile protein. ODC degradation is stimulated by Az (antizyme), a polyamine-induced protein, which in turn is regulated by an ODC-related protein termed AzI (Az inhibitor). Recently, another ODCp (ODC paralogue) was suggested to function as AzI, on the basis of its ability to increase ...

1 Nion Co., 1102 Eight St, Kirkland, WA 98033, USA 2 Center for Solid State Science, Arizona State University, Tempe, AZ 85287, USA 3 Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA 4 School for Engineering of Matter, Transport and Energy, ASU, Tempe, AZ 85287, USA 5 Department of Physics, ASU, Tempe, AZ 85287, USA 6 Department of Physics, University of ...

P. Whalen,1 J. V. Moloney,2,3,4 A. C. Newell,3 K. Newell,3 and M. Kolesik2,4,5 1Program in Applied Mathematics, University of Arizona, Tucson, AZ 85721-0089, USA 2Arizona Center for Mathematical Sciences, University of Arizona, Tucson, AZ 85721-0089, USA 3Department of Mathematics, University of Arizona, Tucson, AZ 85721-0089, USA 4College of Optical Sciences, University of Arizona, Tucson, AZ ...

Guo-Yue Niu,* Peter A. Troch, Claudio Paniconi, Russell L. Scott, Matej Durcik, Xubin Zeng, Travis Huxman, David Goodrich and Jon Pelletier 1 Biosphere 2 Earth Science, University of Arizona, Tucson, AZ, USA 2 Department of Hydrology and Water Resources, University of Arizona, Tucson, AZ, USA 3 Centre Eau Terre Environment, Institut National de la Recherche Scientifique (INRS-ETE), Université d...