psoriasis is a chronic, inflammatory and proliferative skin disease that has a wide distribution throughout the world. the immune system plays a critical role in developing this disease. in this survey, we have studied 50 patients suffering from psoriasis and 50 control subjects for various immunological factors, simultaneously. anti-stratum corneum (sc) antibody was evaluated by immunofluoresc...

Anti- phospholipid syndrome (APS) is an autoimmune prothrombotic disease characterized by persistently elevated antiphospholipid antibodies, resulting in recurrent arterial and venous thromboembolic events. The deep veins of the lower limbs cerebral circulation are most common sites thrombosis, respectively [1] other major clinical manifestations obstetrical. They include unexplained death one ...

The year following parturition is a critical time for the de novo appearance or exacerbation of autoimmune diseases, including autoimmune thyroid disease. The vast majority of postpartum thyroid disease consists of postpartum thyroiditis (PPT) and the minority by Graves' disease and non-autoimmune thyroiditis. PPT has a worldwide prevalence ranging from 1 to 22% and averaging 5% based on a revi...

antiphospholipid antibodies (apla) may be detected in normal pregnancies and also may cause thrombosis, recurrent fetal loss, placental infarction and preeclampsia. in the present study the possible differences in apla titer between healthy pregnant women and preeclampsia cases without history of thrombosis was examined. the apla titer in 50 healthy pregnant women with 50 preeclampsia cases wit...

Pemphigus foliaceus (PF) is an autoimmune blistering disease presenting in endemic and sporadic forms. The typical presentation is recurrent shallow erosions in a seborrheic distribution. PF has also been found in association with autoimmune diseases such as autoimmune thyroid disease (e.g. toxic nodular goiter and Hashimoto’s thyroiditis). In some patients, PF appears to be triggered by radioi...

type i diabetes mellitus (dm) is frequently associated with autoimmune thyroid disease (atd). association of atd and type i dm has been described with varying frequencies but there is still debate about the situation in the iranian population. we investigated the prevalence of anti thyroid peroxidase (anti-tpo) antibodies and atd in children and adolescents with type i dm. a total of 145 patien...

Antiphospholipid antibodies (APLA) may be detected in normal pregnancies and also may cause thrombosis, recurrent fetal loss, placental infarction and preeclampsia. In the present study the possible differences in APLA titer between healthy pregnant women and preeclampsia cases without history of thrombosis was examined. The APLA titer in 50 healthy pregnant women with 50 preeclampsia cases wit...

Autoimmune disease has affected up to 50 million Americans, according to the American Autoimmune Related Diseases Association (AARDA) and 75 percent of those affected are women. These inflammatory diseases have variable activity and a lot of women will have to undergo major therapies during and after pregnancy. Many of the women suffering from these disease will improve during gestation. Howeve...

Background and Objectives: Granulomatous mastitis is a benign disease with clinical presentation similar to that of breast cancer, most commonly observed in women childbearing age. Although it has been suggested autoimmune diseases are involved its pathogenesis, no specific treatments have established. The occurrence this during pregnancy rarely reported. We presented the case 37-year-old woman...