BACKGROUND Several uncontrolled studies of hyperbaric treatment in children with autism have reported clinical improvements; however, this treatment has not been evaluated to date with a controlled study. We performed a multicenter, randomized, double-blind, controlled trial to assess the efficacy of hyperbaric treatment in children with autism. METHODS 62 children with autism recruited from ...

Most early-intervention Autism Spectrum Disorder (ASD) clinical trials are limited by the availability of psychometric technicians who assess each child's abilities before and after therapeutic intervention. If parents could administer regular psychometric evaluations of their children, then the cost of clinical trials will be reduced, enabling longer clinical trials with the larger number of p...

Autism spectrum disorders (ASD) are recognized as a major public health issue. Here, we evaluated the effects of folic acid intervention on methylation cycles and oxidative stress in autistic children enrolled in structured teaching. Sixty-six autistic children enrolled in this open-label trial and participated in three months of structured teaching. Forty-four children were treated with 400 μg...

OBJECTIVE To investigate the possible therapeutic effects of camel milk on behavioral characteristics as an interventional strategy in autistic children. STUDY DESIGN Double-blind, Randomized Clinical Trial (RCT). PLACE AND DURATION OF STUDY Autism Research and Treatment Center, Al-Amodi Autism Research Chair, Department of Physiology, Faculty of Medicine, King Khalid University Hospital, K...

Introduction The goal of research is investigation on the effectiveness of Holistic Multi-dimensional Treatment Model (HMTM) in improvement of CARS test indicators in children with Autism Spectrum Disorder (ASD) and it is done without pharmaceutical interventions, without names and accompanied by parental satisfaction questionnaire. Materials and Methods In this study with purposeful sampling m...

autism is a lifelong neurological disability of unknown etiology. the criteria for a diagnosis of autism are based on a triad of impairments in social interaction, communication and a lack of flexibility in thinking and behavior there are several factors which are likely to contribute to this variation including the definition of autism and variability in diagnosis amongst professionals, howeve...

Abnormal synaptic maturation and connectivity are possible etiologies of autism. Previous studies showed significantly less alpha activity in autism than normal children. Therefore, we studied the effects of anodal tDCS on peak alpha frequency (PAF) related to autism treatment evaluation checklist (ATEC). Twenty male children with autism were randomly assigned in a crossover design to receive a...

abstract: aim and background: autism spectrum disorder is a complex childhood neurological disorder that affects all aspects of child development. the purpose of this study was to determine the effectiveness of an intervention program using animals to improve cognitive, social, behavioral functioning , and communication in children with autism spectrum disorders. methods and materials: 14 child...

The patient, who was high-functioning, presented for evaluation of incomprehension of others' mind, aggressive behavior including self-injury, and marked impairment in social interactions. Her score on the Aberrant Behavior Checklist (ABC), completed by her mother, was 69 (very high), with individual items indicating hyperirritability, aggression, bizarre behaviors, and poor empathy. She receiv...

This exploratory study investigates the contributions the Clinical Risk Indicators in Child Development (CDRI) may bring for the evaluation of infants who might be considered in autistic development. To do so, results of the evaluation – using CDRI and the Modified Checklist for Autism (M-CHAT) – of 43 babies who were 18 months old were compared. The present study showed that autism is amongst ...