Derived-band click-evoked auditory brainstem responses (ABRs) were obtained for normal-hearing (NH) and sensorineurally hearing-impaired (HI) listeners. The latencies extracted from these responses, as a function of derived-band center frequency and click level, served as objective estimates of cochlear response times. For the same listeners, auditory-filter bandwidths at 2 kHz were estimated u...

introduction: hearing is essential for humans to communicate with one another. early diagnosis of hearing loss and intervention in neonates and infants can reduce developmental problems. the aim of the present study was to assess the prevalence of hearing impairment in newborns admitted to a neonatal intensive care unit (nicu) and analyze the associated risk factors.   materials and methods: th...

A 34-year-old female presented to our clinic with complaints of hearing loss, tinnitus, and severe rotational vertigo. A test battery including complete audiometric testing, auditory brainstem response (ABR) audiometry, electronystagmography (ENG), electrocochleography (ECoG), and dehydration testing was performed. Monitoring of hearing sensitivity, speech understanding, and ECoG responses foll...

This article describes some of the factors relevant to the establishment of a universal newborn hearing screening (UNHS) program. First, the difficulty in providing precise estimates of test sensitivity and specificity are reviewed. This section is followed by hypothetical estimates of overall programmatic costs, first for a fixed number of babies to be screened and then as a function of the nu...

UNLABELLED Evidence from animal and human studies suggests that moderate acoustic exposure, causing only transient threshold elevation, can nonetheless cause "hidden hearing loss" that interferes with coding of suprathreshold sound. Such noise exposure destroys synaptic connections between cochlear hair cells and auditory nerve fibers; however, there is no clinical test of this synaptopathy in ...

The human auditory brainstem is thought to undergo rapid developmental changes early in life until age ∼2 followed by prolonged stability until aging-related changes emerge. However, earlier work on brainstem development was limited by sparse sampling across the lifespan and/or averaging across children and adults. Using a larger dataset than past investigations, we aimed to trace more subtle v...

OBJECTIVE To investigate whether the saccule exhibits temporary or permanent functional loss resembling threshold shifts in auditory brainstem response (ABR) of guinea pigs following noise exposure. DESIGN Randomly bred guinea pigs were divided into 3 groups: A (short-term noise exposure, 30 minutes, n = 15), B (long-term noise exposure, 40 hours, n = 9), and C (no noise exposure, n = 5). S...

Biotinidase deficiency is a disorder inherited autosomal recessively showing evidence of hearing loss and optic atrophy in addition to seizures, hypotonia, and ataxia. In the present study, a 2-year-old boy with Biotinidase deficiency is presented in which clinical symptoms have been reported with auditory neuropathy/auditory dyssynchrony (AN/AD). In this case, transient-evoked otoacoustic emis...

INTRODUCTION Alström Syndrome is a rare disease caused by mutations in ALMS1 gene. It is characterized by a progressive degeneration of sensory functions, resulting in visual and audiological impairment, as well as metabolic disturbances such as childhood obesity, hyperinsulinemia, and diabetes mellitus type 2. OBJECTIVE To report and discuss the genetic and audiological findings in two sibli...