Two iridoid glucosides, catalpol and aucubin, one chlorinated iridoid aglycon, rehmaglutin D were isolated from the iridoid fraction of the aerial parts of Plantago lagopus L. together with the megastigman glucoside, phlomuroside. The structures of the isolated compounds were identified by means of spectroscopic (UV, HR-ESI, 1H-NMR, 13C NMR , HMQC, HMBC, COSY) methods. This is the first report ...

BACKGROUND Plantago major has been reported to have anticancer and anti-inflammatory properties. However, its antiproliferative and anti-inflammatory mechanisms have not been fully elucidated. Moreover, which plant parts are more suitable as starting materials has not been explored. OBJECTIVES To investigate the antiproliferative activity of P. major extracts against MCF-7, MDA-MB-231, HeLaS3...

The Glanville fritillary butterfly (Melitaea cinxia) in Finland feeds on the plants Plantago lanceolata and Veronica spicata. These two plant species are distributed heterogeneously and both vary spatially and temporally in iridoid glycoside concentrations. We investigated the associations of plant species and iridoid glycoside (aucubin and catalpol) concentrations with weight, development rate...

A comparative study was performed on 12 species of the genus Veronica L. (Plantaginaceae sensu APG 2003, formerly Scrophulariaceae) namely Veronica persica, V. bachofenii, V. urticifolia, V. agrestis, V. austriaca, V. chamaedrys, V. officinalis, V. orchidea, V. spicata, V. beccabunga, V. hederifolia, V. prostrata. In these species we have determined the aucubin and catalpol content by using a H...

Two new iridoids, 10-O-benzoylglobularigenin (1) and dumuloside (2) were isolated from the aerial parts of Globularia dumulosa together with seven known iridoid glucosides, davisioside (3), aucubin (4), melampyroside (5), catalpol (6), 10-O-benzoylcatalpol (7), alpinoside (8) and deacetylalpinoside (9). Three phenylethanoid glycosides, verbascoside, decaffeoyl-verbascoside, leucosceptoside A an...

A new natural compound, named 6-O-(3",4"-dimethoxycinnamoyl) catalpol, was isolated from the defatted alcoholic extract of the flowering parts of Buddleja asiatica Lour. (family Scrophulariaceae). Other separated known compounds included steroids (beta-sitosterol, stigmasterol, stigmasterol-O-glucoside, beta-sitosterol-O-glucoside), iridoid glucosides (methyl catalpol, catalpol, aucubin), pheny...