zinc has an important role in skin health and its deficiency reduces immunity. to evaluate levels of zinc in squamous cell carcinoma (scc) and basal cell carcinoma (bcc) of skin, we studied 44 bcc and 38 scc cases together with 33 controls. blood samples were taken and after separation of serum, levels of zinc, albumin and total protein were measured by atomic absorption, albumin kit and reflec...

The role of cells expressing stem cell markers deltaNp63 and CD44v has not yet been elucidated in peripheral-type lung squamous cell carcinoma (pLSCC) carcinogenesis. Female A/J mice were painted topically with N-nitroso-tris-chloroethylurea (NTCU) for induction of pLSCC, and the histopathological and molecular characteristics of NTCU-induced lung lesions were examined. Histopathologically, we ...

We collected a series of 136 lung/bronchial and 56 matched lung parenchyma tissue samples from patients who underwent lung/bronchial biopsies and presented invasive carcinoma after lung surgery. The lung/bronchial samples included basal cell hyperplasia, squamous metaplasia, moderate dysplasia, adenomatous hyperplasia, severe dysplasia, squamous cell carcinoma and adenocarcinoma. Matched lung p...

background and aims. several diagnostic methods are being employed to detect benign and malignant lesions, one of which is silver nitrate staining for organizer regions. the number of nucleolar organizing regions (nors) can be used to show the degree of cell activity or metabolism in pathologic lesions. this study was designed to evaluate nors as determinants of precancerous and squamous cell c...

conclusions based on evidence, dentists and dental health care professionals should consider periodontal disease as a risk factor for the development of neoplasms in the oral cavity. it also seems a good idea to provide periodontal therapy for patients with cancer to achieve ideal therapeutic results. results cancer of the oral cavity and periodontal disease are related from different aspects. ...

this is a case report concerning a 60 years old man who lived for a short period in an endemic area of khuzestan province (neighboring province of persian gulf in iran) for approximately 20 years ago. recently he referred to the urology department of kerman university of medical sciences with hematuria and dysuria. in the sonography a polypoid mass on the bladder floor was observed. in the cyst...

skin cancer is one of the most important type of cancers in the world. in this way, molecular investigation in order to detect some novel mechanisms and polymorphisms involved in cancer development can be impressive and vital. in this way, the aim of this study was the histopathological investigation of skin cancer and its relationship with polymorphism of cdkn2a gene. this case-control study w...

Cemiplimab is the first PD-1 inhibitor approved in United States for treatment of metastatic or locally advanced cutaneous squamous cell carcinoma (SCC) and basal (BCC), but not melanoma. We describe a case amelanotic melanoma (AM) developing patient on cemiplimab therapy invasive SCC. Cutaneous AM rare subtype that shows little no melanin pigmentation clinical histological examination thus oft...

of the esophagus: narrow-band imaging and dual focus magnification Endoscopic examination with virtual chromoendoscopy is currently the best way to distinguish squamous cell carcinoma and adenocarcinoma in the esophagus [1,2]. However, some unusual tumors such as adenoid cystic carcinoma can have atypical endoscopic features. A 65-year-oldmanwas referredbecause of an atypical esophageal neoplas...

A 73-year-old woman was found to have a 1.7 cm axillary mass, for which a core needle biopsy was performed. The specimen revealed fragmented squamous epithelium surrounded by lymphoid tissue consistent with a squamous inclusion cyst in a lymph node, but a metastatic squamous cell carcinoma could not be excluded. Within one month, the lesion enlarged to 5 cm and was excised. Touch preparation cy...