Background. Parathyroid adenoma is the commonest cause of primary hypercalcaemia and usually presents with symptoms/signs of hypercalcaemia. This paper highlights an unusual presentation. Case Report. A 27-year-old female presented with a painful left mandibular swelling, suspicious of neoplasia. A computed tomography (CT) guided biopsy was performed. Based on the histology result, serum calciu...

Background. Parathyroid carcinoma is an infrequent clinical entity whose diagnosis is very challenge. Indeed a pre-operative or intraoperative diagnosis of parathyroid carcinoma is reported in less than half cases described in the literature. Patients and Methods. A systematic review of pathological reports of our secondary referral hospital was done. From 2003 to 2011 one hundred and forty-fou...

Parathyroid adenomas are benign encapsulated neoplasms that are typically comprised of chief cells and feature a rim of normal parathyroid tissue at their periphery. A small subset can be classified as atypical based on the presence of some histologic features of malignancy, such as a trabecular growth pattern, increased mitotic activity, capsular invasion, and fibrous bands, without definitive...

Primary hyperparathyroidism is a generalized disorder of bone and mineral metabolism caused by autonomous secretion of parathyroid hormone. It is primarily seen in adults with typical age of presentation between third and fifth decades of life. Juvenile hyperparathyroidism is a rare disorder. The common presentations in order of incidence are fatigue and lethargy, headache, nephrolithiasis, nau...

Localization of 99mTc- hexakis-2-methoxyisobutylisonitrile (99mTc-MIBI) by parathyroid adenomas is well known, and this warrants MIBI scan to evaluate suspected parathyroid adenoma in primary hyperparathyroidism. Typically, the radionuclide concentrates in both the thyroid gland and parathyroid adenoma in early images, and later on delayed images washes out slowly from the...

conclusions radiofrequency ablation may be used successfully in the treatment of parathyroid adenoma when a patient cannot tolerate surgery. case presentation a 47-year-old patient was referred to our hospital (namazi hospital, shiraz, iran) in april, 2015 with intracranial hemorrhage, as well as high serum calcium and pth (parathyroid hormone) levels (12.1 mg/dl and 1062 pg/ml, respectively), ...

Brown tumors seen in hyperparathyroidism are rare, non-neoplastic lesions because of abnormal bone metabolism, and they can mimic benign bone tumors or malignancy. Although biopsy is considered as the gold standard for diagnosis, it can be inconclusive. As the diagnosis of brown tumors is often challenging, a high index of suspicion is essential for diagnosis. We present a case of 21-year-old w...

the coexistence of medullary thyroid carcinoma (mtc), papillary thyroid carcinoma (ptc) and parathyroid adenoma is an uncommon clinical entity. here, we report a case of mtc, ptc, and parathyroid adenoma diagnosed incidentally on a routine physical examination of the neck for the work-up of diabetes. the patient had neither symptoms of hypercalcemia nor those related to mtc and ptc.