While studying animal-based measures to be included in the welfare assessment protocols, researchers often identify potential welfare indicators that do not fulfil the standards. This could be due to low prevalence, ambiguous meaning, lack of interobserver repeatability, or unknown or controversial validity. In this talk we will present some potentially useful welfare indicators that have not b...

Pilomatricoma or benign calcifying epithelioma of Malherbe is a benign appendageal tumour originating from primitive cells of the hair matrix. Perforation (transepidermal elimination), bullous or anetodermic cutaneous changes overlying pilomatricomas are rare events. In this report, we describe a case of pilomatricoma with bullous appearance or secondary anetoderma. The tumour was totally excis...

OBJECTIVES Enthesitis is one of the most common and specific manifestations of ankylosing spondylitis (AS). However, the treatment of enthesitis is still a challenge for rheumatologist so far, especially to those AS patients with serious enthesitis. This study aimed to evaluate the efficacy and safety of ultrasound (US)-guided local injection of etanercept into entheses of AS patients with refr...

It is known that the brain's resting-state activity (RSA) is organized in low frequency oscillations that drive network connectivity. Recent research has also shown that elements of RSA described by high-frequency and nonoscillatory properties are non-random and functionally relevant. Motivated by this research, we investigated nonoscillatory aspects of the blood-oxygen-level-dependent (BOLD) R...