Astragalus L., is one of the largest genus of flowering plants in the Leguminosae family. The aim of this study was to review anti-carcinoma activities of this valuable herb. This review article was carried out by searching studies in PubMed, Medline, Web of Science, and Iran Medex databases .The initial search strategy identified about 128 references. In this study, 113 studies was accepted fo...

This study was conducted to evaluate the antimicrobial and antioxidant activities of the hexane and methanol extracts of the aboveground parts and roots of some Astragalus species grown in the vicinity of Erzurum, located in the eastern Anatolia, Turkey. The methanol extract, which was obtained from the aboveground parts of Astragalus species, exhibited mild free radical scavenging activity pro...

Owing to a dramatic increase in average life expectancy and the Family Planning program of the 1970s - 1990s, China is rapidly becoming an aging society. Therefore, the investigation of healthspan-extending drugs becomes more urgent. Astragalus membranaceus (Huangqi) is a major medicinal herb that has been commonly used in many herbal formulations in the practice of traditional Chinese medicine...

Aims. To explore whether Astragalus or its formulations could prevent upper respiratory infection in children with nephrotic syndrome and how best to use it. Methods. We transformed a common clinical question in practice to an answerable question according to the PICO principle. Databases, including the Cochrane Library (Issue 5, 2012), PUBMED (1966-2012.8), CBM (1978-2012.8), VIP (1989-2012.8)...

Honey-processed Astragalus is a dosage form of Radix Astragalus mixed with honey by a traditional Chinese medicine processing method which strengthens the tonic effect. Astragalus polysaccharide (APS), perform its immunomodulatory effects by relying on the tonic effect of Radix Astragalus, therefore, the improved pharmacological activity of honey-processed Astragalus polysaccharide (HAPS) might...

Some species hyperaccumulate selenium (Se) upwards of 0.1% of dry weight. This study addressed whether Se hyperaccumulators also accumulate and tolerate more molybdenum (Mo). A field survey revealed on average 2-fold higher Mo levels in three hyperaccumulator Astragali compared to three nonaccumulator Astragali, which were not significantly different. Next, a controlled study was performed wher...

Astragalus mongholicus Bunge has long been used to treat cardiovascular disease in Chinese traditional medicine. However, its mechanisms are not fully understood. In this study, we explored potential mechanisms and protective effects of total flavonoids of Astragalus (TFA) on cardiovascular disease using in vitro experiments and diet-induced atherosclerotic rabbits. We identified six components...

This study carried out for determination and discrimination of intraspecific diversity of Astragalus verus and Astragalus glaucops by Eco-phytosociological method from west of Iran. In this order, application of Endogenous milieu (special station) for data collecting and then their analyzing permit us only determine existence of inter and intraspecific diversity. Then for determinating kind and...

Radix Astragali has been an important traditional Chinese herbal medicine for over 2000 years. It is derived from two plant species, namely, Astragalus mongholicus [Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.) Hsiao] and Astragalus membranaceus [Astragalus membranaceus (Fisch.) Bge.] (Leguminosae), according to the Pharmacopoeia of the People’s Republic of China. In this study,...

Background. Radiotherapy has been widely used for non-small-cell lung cancer (NSCLC), while its low efficacy and high toxicity raise big concerns. Astragalus (as a monarch drug)-containing Chinese herbal prescriptions and radiotherapy were frequently coused for NSCLC in China; however, the effects were not systematically analyzed. Objective. To evaluate the benefits of Astragalus-containing Chi...