fertilization involves direct interaction of the sperm and oocyte, fusion of the cell membranes and :union: of male and female gamete genomes. the completion of this process and subsequent embryo development depend in part on the inherent integrity of the sperm dna. sperm genome quality has been emphasized for several years as playing a major role in early embryogenesis. there is clinical evide...

background:   objective: comparison of albumin and cabergoline in the prevention of ohss.   materials and methods: 95 high risk infertile women for ohss (more than 20 follicles in both ovaries at day of human chorionic gonadotropin (hcg) injection) were randomly divided into two groups. first group including 48 women received 10 unit intravenous albumin at starting oocyte retrieval, and second ...

in vitro fertilization (ivf) and other assisted reproductive technologies present an enormous hope to couples with fertility difficulties. assisted reproductive technology is one of the risk factors that can result in anxiety in these couples. indeed, ivf-treatments cause a stress, for both the woman and her partner. the different stages of the ivf-procedure can affect the emotional life of the...

objective: there is a large amount of information published about art infants worldwide but apparently the similar data did not published by iranian art centers till now. this study is a comparative study for developmental assessment of these infants. materials and methods: in one case- control study 400 art ' infants have been compared with 420 nc ' infants. their developments have been assess...

background: implantation failure of blastocyst is one of the main reasons of failure to become pregnancy following use of assisted reproductive techniques. hla-g, one of the non-classic hla subtypes, seems to have a vital role in neutralizing of mother immune system. according to importance of ins/del polymorphism of hla-g in regulation of hla-g expression, it seems that this polymorphism has a...

background: despite numerous developments in the field of assisted reproduction the implantation rate remains low .recent studies suggested that local injury to endometrium in controlled ovarian hyper stimulation cycle improves implantation rate. studies have attempted to intervene in the development of endometrium. objective: the aim of the present study was the exploration of the possibility ...

Varicocele-associated male infertility has classically been managed using surgery or assisted reproductive techniques. With increasing evidence of oxidative stress as a pathophysiological factor in varicocele-associated infertility, medical therapy especially antioxidants might become a treatment option with lower risks. We reviewed the existing literature on the role of various medical agents ...

We report a case of polycystic ovary syndrome and prolonged infertility in which endometrial intraepithelial neoplasia was reversed with high dose progesterone therapy. Spontaneous conception after failure of assisted reproductive techniques highlights the role of endometrial receptivity.

Assisted reproductive technology (ART) programs are complex organizations requiring the integration of multiple disciplines. ISO 9001:2008 is a quality management system that is readily adaptable to an ART program. The value that ISO brings to the entire organization includes control of documents, clear delineation of responsibilities of staff members, documentation of the numerous processes an...