pregabalin (prg) is a new antiepileptic drug and aceclofenac (ace) is a potent non-steroidal anti-inflammatory drug. these drugs in combination are used for treatment of partial seizures and neuropathic pains. a simple and precise assay method by rp-hplc was developed and validated for estimation of prg and ace in acenac-n tablet. analyses of commercial tablet, acenac-n were performed using jas...

low molecular weight organic acids are most predominant in apple juice among these components fumaric acid was not exceed more than 5 ppm. it was thought that the hplc is the best method of the determination of organic acids in the apple juice. in this study, chromatographic separation of organic acids of apple juice was obtained by preparing a sample and by applying them to acid phase for extr...

an environmentally benign rp-hplc approach for rapid analysis of glibenclamide in pure form, developed nanoemulsion and commercial tablets was developed and validated in present investigation. the green chromatographic identification was performed on lichrosphere 250 x 4.0 mm rp c8 column having a 5µm packing as a stationary phase using a combination of ethanol: methanol (50:50 % v/v) as a mobi...

A convenient and accurate reversed-phase high-performance liquid chromatography (RP-HPLC) method for angiotensin I-converting enzyme inhibitory peptides assay was described in this paper. The mobile phase consisted of 70% A (0.05% TFA and 0.05% triethylamine in water, pH = 2.9-3.3) and 30% B (100% acetonitrile) using an Isogradient program. The flow rate was 0.5 mL/min. The absorb wavelength wa...

RP-HPLC METHOD DEVELOPMENT FOR THE QUANTIFICATION OF GABAPENTIN IN FORMULATIONS ABSTRACT A simple, precise and accurate RP-HPLC method was developed and validated for rapid assay of Gabapentin in tablet dosage form. Isocratic elution at a flow rate of 1 mL/min was employed on a symmetry Zodiac C18 (250mmx4.6mm,I.D., 5μm particle size) at ambient temperature. The mobile phase consisted of Methan...