Pulmonary aspergillosis in nonimmunocompromised hosts, although rare, is being increasingly recognized. The diagnosis of pulmonary aspergillosis is difficult, since the recovery of Aspergillus from respiratory samples cannot differentiate colonization from invasion. We assessed the role of bronchoalveolar lavage (BAL) in detecting galactomannan (GM) for diagnosing pulmonary aspergillosis in 73 ...

Liposomal amphotericin B (LAmB) combined wither either micafungin or deferasirox was synergistic in previous murine studies with mucormycosis or aspergillosis. We hypothesized that triple therapy using LAmB, micafungin, and deferasirox could further improve outcomes of mucormycosis or aspergillosis. Triple therapy improved survival and reduced tissue fungal burden of mice with mucormycosis and ...

OBJECTIVE To evaluate the clinical and radiographic features of pulmonary aspergillosis as they present in AIDS patients; in particular, to determine similarities and differences between Aspergillus infection in patients with AIDS vs those without AIDS. SUBJECTS AND METHODS Six new cases of confirmed or probable pulmonary aspergillosis were discovered during a search of hospital records. Thes...

a 32-year-old end stage renal disease (esrd) woman was scheduled for transplantation. also, she has had fever of unknown origin (fuo), rise of esr and ppd>22 mm. therefore treatment with isoniazid and rifampin was started three months prior to transplantation. she developed allograft dysfunction on week after transplantation. she received a few course pulse therapy (methyl prednisolone), antily...

Major progress for the management of invasive aspergillosis has come from the introduction of new antifungals since the late 1990s. Although mortality of invasive aspergillosis remains as high as 30-50%. Backbone of management are prophylaxis, early diagnosis and early initiation of antifungals for reduction of invasive aspergillosis related mortality. Randomized trials have been undertaken for...

Invasive aspergillosis is a severe opportunistic infection with high mortality in immunocompromised patients. Recently, the roles of microRNAs have been taken into consideration in the immune system and inflammatory responses. Using bioinformatics approaches, we aimed to study the microRNAs related to invasive aspergillosis to understand the molecular pathways involved in the disease pathogenes...

Chronic necrotizing pulmonary aspergillosis (CNPA) is a rare form of pulmonary aspergillosis. The radiological findings in CNPA are very diverse. We present a mildly imunosuppresive, elderly 71-year-old woman with the diagnosis of chronic necrotizing pulmonary aspergillosis presenting as transient migratory thoracic mass.

Primary laryngeal aspergillosis in immunocompetent patients is rare. We describe a case of a 59-year-old woman with laryngeal aspergillosis thought to be secondary to long-term inhaled fluticasone therapy. Laryngeal aspergillosis may be an underrecognized complication of inhaled corticosteroid therapy.

introduction: atypical infratemporal fossa infections are rare and potentially fatal.   case report: a case of an aspergillosis localized in the infratemporal fossa and another case of tuberculosis of the infratemporal fossa originating from the maxillary sinus, is described. the first patient was immunocompromised and showed symptoms of facial numbness; whereas the other was an immunocompetent...

Ann Saudi Med 29(1) January-February 2009 www.saudiannals.net 53 Pulmonary aspergillosis frequently complicates existing pulmonary cavity, which is commonly due to tuberculosis.1-6 Pulmonary aspergillosis has also been reported, though rarely, in pulmonary cavities as a consequence of the removal of a hydatid cyst.7-9 We report a case with active pulmonary hydatid disease that was co-infected w...