BACKGROUND Hypoxemia during one-lung ventilation (OLV) remains a major concern. The present study compared the effect of alveolar recruitment strategy (ARS) on arterial oxygenation during OLV at varying tidal volumes (Vt) with or without positive end-expiratory pressure (PEEP). METHODS In total, 120 patients undergoing wedge resection by video assisted thoracostomy were randomized into four g...

Poor water-solubility of artesunate (ARS) hampers its clinical application. We here covalently linked ARS to PEGylated nanographene oxide (nGO-PEG) to obtain ARS-modified nGO-PEG (nGO-PEG-ARS) with excellent photothermal effect and dispersibility in physiological environment. nGO-PEG-ARS induced reactive oxygen species (ROS) and peroxynitrite (ONOO─) generations. Although nGO-PEG with near-infr...

T he 13th International Symposium on Wearable Computers (ISWC) was held last September in Linz, Austria, the European Union’s selected European Cultural Capital for 2009. The city’s new Ars Electronica Center, which opened earlier in the year, provided an excellent venue for ISWC. It also collocated the symposium with the 2009 Ars Electronica Festival. Alois Ferscha and Gerfried Stocker cochair...

Identification of Area-restricted search (ARS) behaviour is used to better understand foraging movements and strategies of marine predators. Track-based descriptive analyses are commonly used to detect ARS behaviour, but they may be biased by factors such as foraging trip duration or non-foraging behaviours (i.e. resting on the water). Using first-passage time analysis we tested if (I) daylight...

1-Adrenergic receptors (ARs) belong to the large Class I G protein-coupled receptor superfamily and comprise three subtypes ( 1A, 1B, and 1D). Previous work with heterologously expressed C-terminal green fluorescent protein (GFP)-tagged 1-ARs showed that 1Aand 1B-ARs localize to the plasma membrane, whereas 1D-ARs accumulate intracellularly. We recently showed that 1Dand 1B-ARs form heterodimer...

DNA replication origins, specified by ARS elements in Saccharomyces cerevisiae, play an essential role in the stable transmission of chromosomes. Little is known about the evolution of ARS elements. We have isolated and characterized ARS elements from a chromosome III recovered from an alloploid Carlsberg brewing yeast that has diverged from its S. cerevisiae homeologue. The positions of seven ...

OBJECTIVES To describe the frequency of adverse reactions (ARs) after transfusion on both per transfused patient and per transfused unit bases. METHODS We performed a retrospective analysis of data available from records of 6 hospitals on the total number of transfusions and documented ARs between January 2008 and December 2009 for RBCs, fresh-frozen plasma (FFP), and platelet concentrates (P...