BACKGROUND Aristolochic Acids (AAs) are major components of plants in Aristolochia and have been found to be nephrotoxic, carcinogenic and mutagenic. Herein reported are the isolation, identification and quantity determination methods of Aristolochic Acid-I (AA-I) and Aristolochic Acid-II (AA-II) toxic compounds of Aristolochia bracteolata indigenous to Central Sudan and medicinally used in div...

Aristolochia indica is one of the important medicinal plant sources of bioactive compound aristolochic acid (AA). The compound was found to produce cytotoxicity at higher doses, thus AA was examined for therapeutic efficacy against 4-nitroquinoline 1-oxide (4-NQO) induced oral cancer. Purity of the isolated AA was assayed using UV, IR, NMR, Mass spectral studies were revealed that the maximum w...

BACKGROUND AND OBJECTIVES Adhesion and colonization are prerequisites for the establishment of bacterial pathogenesis. The biofilm development of Pseudomonas aeruginosa was assessed on adhesive surfaces like dialysis membrane, stainless steel, glass and polystyrene. MATERIALS AND METHODS Microtiter plate biofilm assay was performed to assess the effect of nutrient medium and growth parameters...

The present study emphasizes to reveal the antivenom activity of Aristolochia bracteolata Lam., Tylophora indica (Burm.f.) Merrill, and Leucas aspera S. which were evaluated against venoms of Daboia russelli russelli (Russell's viper) and Naja naja (Indian cobra). The aqueous extracts of leaves and roots of the above-mentioned plants and their polyherbal (1 : 1 : 1) formulation at a dose of 200...

The genus Aristolochia,an important source of physiologically active compounds that belong to different chemical classes, is the subject of research in numerous pharmacological and chemical studies. This genus contains a large number of terpenoid compounds, particularly diterpenes. This work presents a compilation of the 13C-NMR data of 57 diterpenoids described between 1981 and 2007 which were...

Aristolochia sinoburmanica Y.H.Tan & B.Yang, a new species of Aristolochiaceae from Putao, Kachin State, Myanmar, is described and illustrated. According to morphology (strongly curved perianth, 3-lobed limb, as well as 3-lobed gynostemium, anthers 6, adnate in 3 pairs to the base of gynostemium, opposite to the lobes), the species belongs to Aristolochia subgenus Siphisia. It is morphologicall...