نتایج جستجو برای: arginine methyl ester

تعداد نتایج: 159012  

Introduction: Nitric oxide (NO), as a free radical, involves in several physiologic functions in GI tract such as nerve impulse transmission and vascular tonicity regulation. Nitric oxide synthase (NOS) is the enzyme for the production of NO from L-Arginine which in turn inhibits by L-NGNitroarginine Methyl Ester (L-NAME). In the current work, we aimed to evaluate morphometric analysis of...

Journal: :Anesthesiology 2008
Katsutoshi Nakahata Hiroyuki Kinoshita Keiko Hama-Tomioka Yuko Ishida Naoyuki Matsuda Noboru Hatakeyama Masanori Haba Toshikazu Kondo Yoshio Hatano

BACKGROUND An acetylcholinesterase inhibitor donepezil currently is used to treat patients with Alzheimer disease. However, its direct effect on cerebral blood vessels has not been evaluated. The present study was designed to examine whether donepezil induces acute cerebral arteriolar dilation and whether neuronal nitric oxide synthase contributes to this vasodilator response. METHODS Brain s...

2005
CHRISTOPHER W. WHARTON KEITH BROCKLEHURST ERIC M. CROOK

1. N-Benzoyl-L-serine methyl ester was synthesized and evaluated as a substrate for bromelain (EC 3.4.22.4) and for papain (EC 3.4.22.2). 2. For the bromelain-catalysed hydrolysis at pH 7.0, plots of [SO]/vi (initial substrate concn./initial velocity) versus [SO] are markedly curved, concave downwards. 3. Analysis by lattice nomography of a modifier kinetic mechanism in which the modifier is su...

Journal: :basic and clinical neuroscience 0
mohammad-reza zarrindast bita hamidi mohammad sharifzadeh mousa sahebgharani soheila fazli-tabaei

in the present study, interactions between lead exposure with nitric oxide precursor (l-arginine) or nitric oxide synthase (nos) inhibitor (l-name) on naloxone-induced jumping and diarrhea in morphine-dependent mice were examined. chronic lead acetate (0.05%) exposure altered naloxone-induced jumping and diarrhea in mice. jumping was decreased after 7 days and was unchanged 14 and 28 days after...

ژورنال: اعتیاد پژوهی 2011
جلالی ندوشن, محمدرضا , رحیم پور, مهناز , کرمی, منیژه ,

Introduction: Previous studies shows L-arginin (nitric oxide precursor) increases conditioned place preference and drug seeking behaviors whereas LG-nitro-arginine methyl ester) L-NAME( as nitric oxide synthase inhibitor decreases this process. In this project, effects of intra-central amygdale bilateral injection of nitric oxide agents on drug-seeking behaviors including rearing, sniffing and ...

Journal: :journal of agricultural science and technology 2010
b. ghobadian h. rahimi t. tavakkoli hashjin m. khatamifar

biofuels are the main substitute to fossil fuels. these fuels are less polluting in compari-son to fossil fuels and can be produced from agricultural material residues for use in die-sel engines. in this research work bioethanol was produced from potato waste. it was de-hydrated in a vapor phase using 3a zeolite and was used in combination with sunflower methyl ester oil and diesel fuel blendin...

Journal: :The American journal of physiology 1997
Xiao-Pei Gao Israel Rubinstein

The purpose of this study was to determine whether methotrexate modulates bradykinin-induced increase in macromolecular efflux from the in situ oral mucosa and whether this response is mediated by thel-arginine/nitric oxide biosynthetic pathway. Using intravital microscopy, we found that suffusion of methotrexate alone onto the hamster cheek pouch had no significant effects on leaky site format...

Journal: :Clinical and experimental hypertension 2012
Arif-Ullah Khan Riaz Ullah Asifullah Khan Mohamad Rais Mustafa Javid Hussain Dharmani Devi Murugan A Hamid Bin A Hadi

This study describes the vasorelaxant potential of some pure compounds isolated from Phlomis bracteosa L. marrubiin, phlomeoic acid, and two new constituents labeled as RA and RB. In rat thoracic aortic rings denuded of endothelium, marrubiin, phlomeoic acid, RA, and RB caused relaxation of high K(+) (80 mM) and phenylephrine (1 μM)-induced contractions at the concentration range of 1.0-1000 μg...

Journal: :iranian biomedical journal 0
منیژه کرمی manizheh karami محسن کریمیان عظیمی mohsen karimian azimi محمدرضا زرین دست mohammad reza zarrindast زینب خلجی zeinab khalaji

background: role of nitric oxide (no) in morphine-induced conditioned place preference (cpp) has already been proposed in the rat medial septum (ms), but no molecular evidence has been provided to clear this fact. methods: effects of intraseptal injections of l-arginine and/or ng-nitro-l-arginine methyl ester (l-name) on morphine place conditioning in wistar rats were examined. morphine (2.5-7....

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه شاهد - دانشکده علوم پایه 1389

شواهد نشان می دهد که بین تقویت مثبت اپیوئیدها و وابستگی دارویی ارتباط وجود دارد. از مرفین جهت القاء ترجیح مکانی شرطی شده و از نالوکسون برای تظاهر وابستگی دارویی به مرفین استفاده می شود. در این پژوهش، اثرات تزریق (l-name) ng- nitro-l- arginine methyl ester به عنوان مهارگر آنزیم نیتریک اکساید سینتاز و l – آرژینین به عنوان پیش ساز نیتریک اکساید به داخل هسته مرکزی آمیگدال، بر بیان ترک القاء شده با ...

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