For many years now, there is a growing interest around ROC curve for characterizing machine learning performances. This is particularly due to the fact that in real-world problems misclassification costs are not known and thus, ROC curve and related metrics such as the Area Under ROC curve (AUC) can be a more meaningful performance measures. In this paper, we propose a SVMs based algorithm for ...

background assessment of glomerular filtration rate (gfr) by common creatinine-based methods is potentially inaccurate in patients with cirrhosis. cirrhotic patients have several underlying conditions that contribute to falsely low serum creatinine concentrations, even in the presence of moderate to severe renal impairment. therefore creatinine-based methods usually overestimate true gfr in the...

Risk assessment is now regarded as a necessary competence in psychiatry. The area under the curve (AUC) statistic of the receiver operating characteristic curve is increasingly offered as the main evidence for accuracy of risk assessment instruments. But, even a highly statistically significant AUC is of limited value in clinical practice.

For many years now, there is a growing interest around ROC curve for characterizing machine learning performances. This is particularly due to the fact that in real-world problems misclassification costs are not known and thus, ROC curve and related metrics such as the Area Under ROC curve (AUC) can be a more meaningful performance measures. In this paper, we propose a quadratic programming bas...

two sensitive spectrophotometric methods are presented for the assay of repaglinide in bulkdrug and in formulations using methyl orange, as reagents. oxidant by reacting with a fixedamount of either methyl orange and measuring the absorbance at 485.2 nm (method-i) andmeasuring the absorbance at 618.9 nm (method-ii). developed method is based on the formationof extractable colored complex of dru...

Allogeneic hematopoietic stem cell transplantation (AHSCT) is a major method of treatmentfor different hematologic and congenital disease. Graft versus host disease (GvHD) is a lifethreateningadverse effect of AHSCT. Cyclosporine is the most important and common agentfor GvHD prophylaxis. Because of variable and unpredictable pharmacokinetics of cyclosporinethat produces...

The area under the ROC curve (AUC) has been widely used to measure ranking performance for binary classification tasks. AUC only employs the classifier’s scores to rank the test instances; thus, it ignores other valuable information conveyed by the scores, such as sensitivity to small differences in the score values. However, as such differences are inevitable across samples, ignoring them may ...